Novel insights on human NK cells' immunological modalities revealed by gene expression profiling
As part of the innate immune system, human NK cells play a critical role early in the systemic
host defense against pathogens and tumor cells. Recent studies suggest a more complex …
host defense against pathogens and tumor cells. Recent studies suggest a more complex …
[HTML][HTML] New aspects of NK cell subset identification and inference of NK cells' regulatory capacity by assessing functional and genomic profiles
E Wilk, K Kalippke, S Buyny, RE Schmidt, R Jacobs - Immunobiology, 2008 - Elsevier
Natural killer (NK) cells represent important early effector cells of the innate immune system.
They can lyse virally infected and malignant cells without prior sensitization, making them …
They can lyse virally infected and malignant cells without prior sensitization, making them …
Cutting edge: human CD49e− NK cells are tissue resident in the liver
HX Aw Yeang, SJ Piersma, Y Lin, L Yang… - The Journal of …, 2017 - journals.aai.org
Most knowledge on NK cells is based on studies of what are now known as conventional NK
cells in the mouse spleen or human peripheral blood. However, recent studies in mice …
cells in the mouse spleen or human peripheral blood. However, recent studies in mice …
Gene and protein characteristics reflect functional diversity of CD56dim and CD56bright NK cells
Recent findings underline the role of NK cell subsets in regulating adaptive immunity. To
define characteristics of NK cell subpopulations, purified CD56dim and CD56bright NK cells …
define characteristics of NK cell subpopulations, purified CD56dim and CD56bright NK cells …
Proteome analysis of human CD56neg NK cells reveals a homogeneous phenotype surprisingly similar to CD56dim NK cells
J Voigt, DFG Malone, J Dias… - European Journal of …, 2018 - Wiley Online Library
Abstract NK cells lacking CD56 (CD56neg) were first identified in chronic HIV‐1 infection.
However, CD56neg NK cells also exist in healthy individuals, albeit in significantly lower …
However, CD56neg NK cells also exist in healthy individuals, albeit in significantly lower …
Genome-wide analyses and functional profiling of human NK cell lines
JT Gunesch, LS Angelo, S Mahapatra, RP Deering… - Molecular …, 2019 - Elsevier
Natural killer (NK) cell lines, including YTS, NK92, NK3. 3, and NKL, represent excellent
models for the study of human natural killer cells. While phenotypic and functional …
models for the study of human natural killer cells. While phenotypic and functional …
Regulatory NK-cell functions in inflammation and autoimmunity
A Lünemann, JD Lünemann, C Münz - Molecular medicine, 2009 - Springer
Natural killer (NK) cells were viewed traditionally as cytotoxic effector cells whose rapid
killing of infected and transformed cells without preactivation provides a first line of defense …
killing of infected and transformed cells without preactivation provides a first line of defense …
Genetic and environmental determinants of human NK cell diversity revealed by mass cytometry
Natural killer (NK) cells play critical roles in immune defense and reproduction, yet remain
the most poorly understood major lymphocyte population. Because their activation is …
the most poorly understood major lymphocyte population. Because their activation is …
Organ-specific phenotypic and functional features of NK cells in humans
Natural killer (NK) cells kill virus-infected and tumor target cells without prior sensitization.
Each NK cell expresses a multitude of activating and inhibitory receptors, and the interplay …
Each NK cell expresses a multitude of activating and inhibitory receptors, and the interplay …
Models to study NK cell biology and possible clinical application
AE Zamora, SK Grossenbacher… - Current protocols in …, 2015 - Wiley Online Library
Natural killer (NK) cells are large granular lymphocytes of the innate immune system,
responsible for direct targeting and killing of both virally infected and transformed cells. NK …
responsible for direct targeting and killing of both virally infected and transformed cells. NK …