[HTML][HTML] Propionibacterium acnes and lipopolysaccharide induce the expression of antimicrobial peptides and proinflammatory cytokines/chemokines in human …

I Nagy, A Pivarcsi, K Kis, A Koreck, L Bodai… - Microbes and …, 2006 - Elsevier
Acne is a common skin disorder of the pilosebaceous unit. In addition to genetic, hormonal
and environmental factors, abnormal colonization by Propionibacterium acnes has been …

[HTML][HTML] Distinct strains of Propionibacterium acnes induce selective human β-defensin-2 and interleukin-8 expression in human keratinocytes through toll-like …

I Nagy, A Pivarcsi, A Koreck, M Széll, E Urbán… - Journal of Investigative …, 2005 - Elsevier
Acne is a chronic inflammatory disease of the pilosebaceous follicle. One of the main
pathogenetic factors in acne is the increased proliferation of Propionibacterium acnes (P …

[HTML][HTML] Recent advances in understanding Propionibacterium acnes (Cutibacterium acnes) in acne

E Platsidaki, C Dessinioti - F1000Research, 2018 - ncbi.nlm.nih.gov
The skin commensal Propionibacterium acnes, recently renamed Cutibacterium acnes,
along with the other major pathophysiological factors of increased seborrhea …

[HTML][HTML] Antibodies elicited by inactivated propionibacterium acnes-based vaccines exert protective immunity and attenuate the IL-8 production in human sebocytes …

T Nakatsuji, YT Liu, CP Huang, RL Gallo… - Journal of Investigative …, 2008 - Elsevier
Propionibacterium acnes is a key pathogen involved in the progression of inflammation in
acne vulgaris. We examined whether vaccination against P. acnes suppressed P. acnes …

Short-chain fatty acids from Cutibacterium acnes activate both a canonical and epigenetic inflammatory response in human sebocytes

JA Sanford, AM O'Neill, CC Zouboulis… - The Journal of …, 2019 - journals.aai.org
The regulation of cutaneous inflammatory processes is essential for the human skin to
maintain homeostasis in the presence of the dense communities of resident microbes that …

Endocrinology and immunology of acne: Two sides of the same coin

CC Zouboulis - Experimental Dermatology, 2020 - Wiley Online Library
Current experimental research on acne pathophysiology has revealed a more complicated
background than the classically reported four‐factor aetiology. Cells of the pilosebaceous …

[HTML][HTML] Different Propionibacterium acnes phylotypes induce distinct immune responses and express unique surface and secreted proteomes

Y Yu, J Champer, GW Agak, S Kao, RL Modlin… - Journal of Investigative …, 2016 - Elsevier
Propionibacterium acnes is a skin commensal bacterium that contributes to the development
of acne vulgaris and other infections. Recent work revealed that P. acnes clinical isolates …

Increased interferon-γ, interleukin-12p40 and IL-8 production in Propionibacterium acnes-treated peripheral blood mononuclear cells from patient with acne vulgaris …

H Sugisaki, K Yamanaka, M Kakeda… - Journal of …, 2009 - Elsevier
BACKGROUND: Acne vulgaris is a multifactorial inflammatory disease of the sebaceous
follicles of the face and torso that frequently occurs in adolescence. Initially, acne starts as a …

What is new in the pathophysiology of acne, an overview

B Dréno - Journal of the European Academy of Dermatology …, 2017 - Wiley Online Library
Acne is a chronic inflammatory disease of the pilosebaceous unit. Its pathophysiology
includes hyperseborrhoea, abnormal follicular keratinization and Propionibacterium acnes …

[HTML][HTML] Propionibacterium acnes and sebaceous lipogenesis: A love–hate relationship?

CC Zouboulis - Journal of Investigative Dermatology, 2009 - Elsevier
In this issue, Iinuma et al. show that Propionibacterium acnes (P. acnes)–conditioned
medium and formalin-killed P. acnes augment intracellular lipid formation in hamster …