Expression of the Y-box protein YB-1 is increased in proliferating normal and cancer cells,
but its role in cell proliferation and cell cycle progression is unclear. We have identified a cell …

Hanahan and Weinberg have proposed the 'hallmarks of cancer'to cover the biological
changes required for the development and persistence of tumours [Hanahan and Weinberg …

Y box binding protein 1 (YB-1) is a protein with a highly conserved cold shock domain (CSD)
that also belongs to the family of DNA-and RNA-binding proteins. YB-1 is present in both the …

Y-box binding protein-1 (YB-1) plays pivotal roles in acquisition of global drug resistance
and cell growth promotion through transcriptional activation of genes for both drug …

Cyclin D1, an oncogenic G1 cyclin, and YB‐1, a transcription factor involved in cell growth,
are both over‐expressed in several human cancers. In human lung cancer, the functional …

In previous studies we identified the transcription/translation factor Y‐box‐binding protein
(YB‐1) as a gene that is upregulated in primary melanoma and melanoma metastases when …

Abstract The Y-box Binding Protein-1 (YB-1) is a highly conserved oncogenic transcription/
translation factor that is expressed in cancers affecting adults and children. It is now believed …

The Y-box binding protein, YB-1, is a member of a DNA binding protein family with a
structurally and functionally conserved cold shock domain. Using Western blotting and …

The p53 tumor suppressor plays a major role in preventing tumor development by
transactivating genes to remove or repair potentially tumorigenic cells. Here we show that …

This review describes the structure and functions of Y-box binding protein 1 (YB-1) and its
homologs. Interactions of YB-1 with DNA, mRNAs, and proteins are considered. Data on the …