Bigger is not better: cortisol-induced cardiac growth and dysfunction in salmonids

IB Johansen, E Sandblom, PV Skov… - Journal of …, 2017 - journals.biologists.com
Stress and elevated cortisol levels are associated with pathological heart growth and
cardiovascular disease in humans and other mammals. We recently established a link …

Short-term cortisol exposure alters cardiac hypertrophic and non-hypertrophic signalling in a time-dependent manner in rainbow trout

KS Nørstrud, MA Vindas, GE Nilsson… - Biology …, 2018 - journals.biologists.com
Cardiac disease is a growing concern in farmed animals, and stress has been implicated as
a factor for myocardial dysfunction and mortality in commercial fish rearing. We recently …

Cortisol response to stress is associated with myocardial remodeling in salmonid fishes

IB Johansen, IG Lunde, H Røsjø… - Journal of …, 2011 - journals.biologists.com
Cardiac disease is frequently reported in farmed animals, and stress has been implicated as
a factor for myocardial dysfunction in commercial fish rearing. Cortisol is a major stress …

Long-term stress induced cortisol downregulation, growth reduction and cardiac remodeling in Atlantic salmon

M Vanhomwegen, G De Boeck… - Journal of Experimental …, 2023 - journals.biologists.com
Stress and elevated plasma cortisol in salmonids have been linked with pathological
remodeling of the heart and deterioration of fitness and welfare. However, these …

Embryo exposure to elevated cortisol level leads to cardiac performance dysfunction in zebrafish

D Nesan, MM Vijayan - Molecular and cellular endocrinology, 2012 - Elsevier
In zebrafish (Danio rerio), de novo cortisol synthesis commences only after hatching,
providing an interesting model to study the effects of maternal stress and abnormal cortisol …

Elevated cortisol lowers thermal tolerance but results in limited cardiac remodelling in rainbow trout (Oncorhynchus mykiss) experiencing chronic social stress

B Bard, A Dodge, W Joyce… - Journal of …, 2021 - journals.biologists.com
Juvenile rainbow trout (Oncorhynchus mykiss) held in pairs form dominance hierarchies in
which subordinate individuals experience chronic social stress accompanied by lowered …

[HTML][HTML] Prolonged cortisol elevation alters whole body and tissue metabolism in rainbow trout (Oncorhynchus mykiss)

T Pfalzgraff, I Lund, PV Skov - … and Physiology Part A: Molecular & …, 2022 - Elsevier
Chronic elevation of circulating cortisol is known to have deleterious effects on fish, but
information about the consequences of prolonged cortisol elevation on the metabolism of …

Early transcriptomic responses associated with the membrane-initiated action of cortisol in the skeletal muscle of rainbow trout (Oncorhynchus mykiss)

JE Aedo, R Zuloaga, M Bastías-Molina… - Physiological …, 2019 - journals.physiology.org
Cortisol is a critical neuroendocrine regulator of the stress response in fish. Cortisol
practically affects all tissues by interacting with an intracellular receptor and modulating …

Acute stress is detrimental to heart regeneration in zebrafish

P Sallin, A Jaźwińska - Open Biology, 2016 - royalsocietypublishing.org
Psychological stress is one of the factors associated with human cardiovascular disease.
Here, we demonstrate that acute perceived stress impairs the natural capacity of heart …

Effects of long-term cortisol treatment on growth and osmoregulation of Atlantic salmon and brook trout

L Vargas-Chacoff, AM Regish, A Weinstock… - General and …, 2021 - Elsevier
Cortisol is the final product of the hypothalamic-pituitary-interrenal (HPI) axis and acts as a
gluco-and mineralo-corticoid in fish. Long-term elevations of cortisol have been linked to …