Effect of schistosomiasis on the outcome of patients infected with HIV-1 starting antiretroviral therapy in rural Tanzania

K Stete, TR Glass, GJ van Dam… - PLoS neglected …, 2018 - journals.plos.org
Background It has been hypothesized that schistosomiasis negatively influences immune
reconstitution in people living with HIV starting antiretroviral therapy (ART). In this study, we …

Schistosomiasis and HIV-1 viral load in HIV-infected outpatients with immunological failure in Tanzania: a case-control study

P Masikini, S Colombe, A Marti, B Desderius… - BMC infectious …, 2019 - Springer
Background Schistosoma sp. infection has been shown to interact with HIV-1 by modifying
susceptibility to the virus and impacting AIDS outcome, but very little is known about the …

Schistosomiasis and impaired response to antiretroviral therapy among HIV-infected patients in Tanzania

L Efraim, RN Peck, SE Kalluvya… - JAIDS Journal of …, 2013 - journals.lww.com
(CD4 counts) and viral loads in HIV-infected patients. 8, 9 Little research has explored the
specific interaction between schistosomiasis and HIV, but 1 study yielded concerning …

Treatment of Schistosoma mansoni Infection Increases Helminth-Specific Type 2 Cytokine Responses and HIV-1 Loads in Coinfected Ugandan Adults

M Brown, PA Mawa, S Joseph… - Journal of Infectious …, 2005 - academic.oup.com
Background. Studies showing that helminths stimulate type 2 cytokine responses and
influence responses to unrelated antigens suggest that helminths may accelerate human …

Schistosomiasis and HIV-1 infection in rural Zimbabwe: effect of treatment of schistosomiasis on CD4 cell count and plasma HIV-1 RNA load

P Kallestrup, R Zinyama, E Gomo… - The Journal of …, 2005 - academic.oup.com
To determine whether treatment of schistosomiasis has an effect on the course of human
immunodeficiency virus type 1 (HIV-1) infection, individuals with schistosomiasis and with or …

Effects of schistosomiasis on susceptibility to HIV-1 infection and HIV-1 viral load at HIV-1 seroconversion: A nested case-control study

JA Downs, KM Dupnik, GJ van Dam… - PLoS neglected …, 2017 - journals.plos.org
Background Schistosomiasis affects 218 million people worldwide, with most infections in
Africa. Prevalence studies suggest that people with chronic schistosomiasis may have …

Comparison of HIV-1 viral loads, CD4-Th2-lymphocytes and effects of praziquantel treatment among adults infected OR uninfected with Schistosoma mansoni in …

HD Mazigo, DW Dunne, D Morona… - Tanzania Journal of …, 2016 - ajol.info
Background: It is hypothesised that Th 2 immunological environment associated with
Schistosoma mansoni infection might favour replication of HIV-1 in co-infected individuals …

Schistosomiasis is associated with incident HIV transmission and death in Zambia

KM Wall, W Kilembe, B Vwalika, C Dinh… - PLoS neglected …, 2018 - journals.plos.org
Background We examined relationships between schistosome infection, HIV transmission or
acquisition, and all-cause death. Methods We retrospectively tested baseline sera from a …

Impact of schistosome infection on long-term HIV/AIDS outcomes

S Colombe, R Machemba, B Mtenga… - PLoS neglected …, 2018 - journals.plos.org
Background Africa bears the burden of approximately 70% of global HIV infections and 90%
of global schistosome infections. We sought to investigate the impact of schistosome …

Praziquantel efficacy against Schistosoma mansoni among HIV-1 infected and uninfected adults living in fishing villages along Lake Victoria, Northwest Tanzania

HD Mazigo, DW Dunne, SM Kinung'hi… - Infectious Diseases of …, 2014 - Springer
Background Animal studies have demonstrated that functional immune responses, as
determined by the levels of CD4+ cell counts and anti-schistosome antibodies responses …