Since urine samples more directly reflect kidney alterations and damage than blood
samples, we investigated whether urine anti-PLA 2 R antibody (uPLA 2 R-Ab) could be …

Aim The phospholipase A2 receptor (PLA2R) is the major target antigen in idiopathic
membranous nephropathy (iMN). The aim of this prospective study was to determine the …

Background: The natural course of idiopathic membranous nephropathy (MN) varies, as it is
known through favorable outcomes in most patients. However, one third of patients with …

Background and objectives The research work in the past years showed that detection of
phospholipase A2 receptor (PLA2R) antigen and its dominant IgG4 autoantibody in …

Background M-type phospholipase A2 receptor (APLA2R) is considered the major antigen
involved in the pathogenesis of adult primary membranous nephropathy (MN), which is the …

Antibodies to the phospholipase A2 receptor 1 (PLA2R1) have been reported in 70% of
cases of idiopathic membranous nephropathy (IMN). The genetic susceptibility of IMN has …

Membranous nephropathy (MN) is the most common cause of nephrotic syndrome in adults,
with an uncertain clinical outcome. The characterization of the phospholipase A 2 receptor …

Abstract Background Although IgG4 deposit against phospholipase A2 receptor (anti-
PLA2R) is predominantly presented in the renal biopsy of patients with primary membranous …

Background Membranous nephropathy (MN) is an autoimmune disease induced by
circulating antibodies against the podocyte protein phospholipase A2 receptor 1 (PLA2R1 …

Background The value of anti-phospholipase A2 receptor antibody (anti-PLA2R ab)
monitoring at 3 months after diagnosis in membranous nephropathy (MN) remains …