Sub-lethal effects induced by a mixture of three non-steroidal anti-inflammatory drugs (NSAIDs) on the freshwater bivalve Dreissena polymorpha

M Parolini, A Binelli - Ecotoxicology, 2012 - Springer
Non-steroidal anti-inflammatory drugs (NSAIDs) are the sixth top-selling drugs worldwide
and are commonly found in freshwater ecosystems in the high ng/l to low μg/l range. Recent …

Chronic effects induced by ibuprofen on the freshwater bivalve Dreissena polymorpha

M Parolini, A Binelli, A Provini - Ecotoxicology and Environmental Safety, 2011 - Elsevier
The sub-lethal effects induced by the non-steroidal anti-inflammatory drug ((NSAID)
ibuprofen (IBU;((±)-2-(p-isobutylphenyl) propionic acid))) were investigated using a battery …

An in vitro biomarker approach for the evaluation of the ecotoxicity of non-steroidal anti-inflammatory drugs (NSAIDs)

M Parolini, A Binelli, D Cogni, C Riva, A Provini - Toxicology in vitro, 2009 - Elsevier
Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most frequently detected
pharmaceuticals in aquatic environments. They are the sixth most sold drugs worldwide and …

Assessment of the Potential Cyto–Genotoxicity of the Nonsteroidal Anti-Inflammatory Drug (NSAID) Diclofenac on the Zebra Mussel (Dreissena polymorpha)

M Parolini, A Binelli, A Provini - Water, Air, & Soil Pollution, 2011 - Springer
A battery of eight biomarkers was used on the freshwater bivalve Dreissena polymorpha in
order to evaluate potential sub-lethal effects of the nonsteroidal anti-inflammatory drug …

[HTML][HTML] Toxic effects of a mixture of pharmaceuticals in Mytilus galloprovincialis: The case of 17α-ethinylestradiol and salicylic acid

M Cunha, MG Silva, L De Marchi, RG Morgado… - Environmental …, 2023 - Elsevier
The impact of pharmaceuticals on marine invertebrates has been a topic of rising concern,
with an increasing number of studies regarding the impacts on bivalves. However, very few …

Multi-biomarker investigation to assess toxicity induced by two antidepressants on Dreissena polymorpha

S Magni, M Parolini, C Della Torre… - Science of the Total …, 2017 - Elsevier
Antidepressants are one of the main pharmaceutical classes detected in the aquatic
environment. Nevertheless, there is a dearth of information regarding their potential adverse …

Ecotoxicological potential of non-steroidal anti-inflammatory drugs (NSAIDs) in marine organisms: bioavailability, biomarkers and natural occurrence in Mytilus …

M Mezzelani, S Gorbi, Z Da Ros, D Fattorini… - Marine environmental …, 2016 - Elsevier
Pharmaceuticals represent a major environmental concern since the knowledge on their
occurrence, distribution and ecotoxicological potential is still limited particularly in coastal …

Transcriptional and cellular effects of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) in experimentally exposed mussels, Mytilus galloprovincialis

M Mezzelani, S Gorbi, D Fattorini, G d'Errico… - Aquatic Toxicology, 2016 - Elsevier
The aim of the present investigation was to provide new insights on accumulation and
possible adverse effects of various non-steroidal anti-inflammatory drugs (NSAIDs) in …

A multi-biomarker assessment of the impact of the antibacterial trimethoprim on the non-target organism Zebra mussel (Dreissena polymorpha)

A Binelli, M Parolini, D Cogni, A Pedriali… - … and Physiology Part C …, 2009 - Elsevier
A battery of eight biomarkers was applied in the freshwater mussel Dreissena polymorpha to
evaluate potential sub-lethal effects of the antimicrobial trimethoprim (TMP, 5-[3, 4, 5 …

Effects of non-steroidal anti-inflammatory drug (NSAID) diclofenac exposure in mussel Mytilus galloprovincialis

M Gonzalez-Rey, MJ Bebianno - Aquatic toxicology, 2014 - Elsevier
In recent years, research studies have increasingly focused on assessing the occurrence of
active pharmaceutical ingredients (APIs) in ecosystems. However, much remains unknown …