[HTML][HTML] Testosterone, risk, and socioeconomic position in British men: Exploring causal directionality

A Hughes, M Kumari - Social Science & Medicine, 2019 - Elsevier
Lower testosterone levels in men are observationally associated with worse health, but it is
unclear whether they contribute to well-established social gradients in health. Mendelian …

Testosterone and socioeconomic position: Mendelian randomization in 306,248 men and women in UK Biobank

S Harrison, NM Davies, LD Howe, A Hughes - Science Advances, 2021 - science.org
Men with more advantaged socioeconomic position (SEP) have been observed to have
higher levels of testosterone. It is unclear whether these associations arise because …

Systematic review and meta-analyses on associations of endogenous testosterone concentration with health outcomes in community-dwelling men

RJ Marriott, J Harse, K Murray, BB Yeap - BMJ open, 2021 - bmjopen.bmj.com
Objectives The overall study aim is to clarify the relation of endogenous sex hormones with
major health outcomes in men. This paper reports a systematic review focusing on …

Investigating the association of testosterone with survival in men and women using a Mendelian randomization study in the UK Biobank

CM Schooling, JV Zhao - Scientific Reports, 2021 - nature.com
Life expectancy in the developed West is currently stagnated and remains shorter in men
than women. Well-established evolutionary biology theory suggests lifespan trades-off …

Endogenous testosterone and mortality in men: a systematic review and meta-analysis

AB Araujo, JM Dixon, EA Suarez… - The Journal of …, 2011 - academic.oup.com
Context: Low testosterone levels have been associated with outcomes that reduce survival
in men. Objective: Our objective was to perform a systematic review and meta-analysis of …

Causal relationship between obesity and serum testosterone status in men: A bi-directional mendelian randomization analysis

J Eriksson, R Haring, N Grarup, L Vandenput… - PloS one, 2017 - journals.plos.org
Context Obesity in men is associated with low serum testosterone and both are associated
with several diseases and increased mortality. Objectives Examine the direction and …

Sex-specific associations of testosterone and genetic factors with health span

X Zhao, S Liang, N Wang, T Hong… - Frontiers in …, 2021 - frontiersin.org
Background Previous studies have suggested associations between testosterone, genetic
factors, and a series of complex diseases, but the associations with the lifespan phenotype …

[HTML][HTML] In and out of unemployment—Labour market transitions and the role of testosterone

P Eibich, R Kanabar, A Plum, J Schmied - Economics & Human Biology, 2022 - Elsevier
Biological processes have provided new insights into diverging labour market trajectories.
This paper uses population variation in testosterone levels to explain transition probabilities …

Sex-specific genetic effects across biomarkers

E Flynn, Y Tanigawa, F Rodriguez, RB Altman… - European Journal of …, 2021 - nature.com
Sex differences have been shown in laboratory biomarkers; however, the extent to which
this is due to genetics is unknown. In this study, we infer sex-specific genetic parameters …

Effects of lifelong testosterone exposure on health and disease using Mendelian randomization

P Mohammadi-Shemirani, M Chong, M Pigeyre… - Elife, 2020 - elifesciences.org
Testosterone products are prescribed to males for a variety of possible health benefits, but
causal effects are unclear. Evidence from randomized trials are difficult to obtain, particularly …