Interdisciplinary studies in the research fields of endocrinology and immunology show that
obesity-associated overnutrition leads to neuroinflammatory molecular changes, in …

The hypothalamus is one of the master regulators of various physiological processes,
including energy balance and nutrient metabolism. These regulatory functions are mediated …

Diet-induced obesity leads to devastating and common chronic diseases, fueling ongoing
interest in determining new mechanisms underlying both obesity and its consequences. It is …

Over the last years, hypothalamic inflammation has been linked to the development and
progression of obesity and its sequelae. There is accumulating evidence that this …

Hypertension is a major health problem with great consequences for public health. Despite
its role as the primary cause of significant morbidity and mortality associated with …

Inflammatory reaction is a fundamental defense mechanism against threat towards normal
integrity and physiology. On the other hand, chronic diseases such as obesity, type 2 …

Stress is accompanied by metabolic alterations that could contribute to the etiology of
diabetes mellitus, arteriosclerosis, and cardiovascular diseases; however, the mechanisms …

Despite numerous educational interventions and biomedical research efforts, modern
society continues to suffer from obesity and its associated metabolic diseases, such as type …

Obesity may be an independent risk factor for coronary artery disease and contribute to a
chronic state of systemic inflammation leading to atherosclerosis and metabolic …

Obesity and its associated metabolic and cardio-vascular disorders are among the most chal-
lenging health problems confronting developed countries. Not only is obesity remarkably …