Tuberculosis (TB) has been a transmittable human disease for many thousands of years,
and M. tuberculosis is again the number one cause of death worldwide due to a single …

Treatment of tuberculosis (TB) remains challenging, with lengthy treatment durations and
complex drug regimens that are toxic and difficult to administer. Similar to the vast majority of …

Tuberculosis (TB) is one of the leading causes of mortality and morbidity, particularly in
developing countries, presenting a major threat to the public health. The currently …

The emergence and spread of drug-resistant strains of Mycobacterium tuberculosis is
worsening the global threat of tuberculosis (TB). There is a need and urgency for the …

The ability of Mycobacterium tuberculosis to cause disease hinges upon successfully
thwarting the innate defenses of the macrophage host cell. The pathogen's trump card is its …

Host-directed therapies are a relatively new and promising approach to treatment of
tuberculosis. Modulation of specific host immune pathways, including those that impact …

In TB, combat between the human host and Mycobacterium tuberculosis involves intricate
interactions with immune cells. M. tuberculosis has evolved a complex evasion system to …

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a leading cause of
morbidity and mortality in humans worldwide. Currently, the standard treatment for TB …

Tuberculosis (TB) is a slow growing, potentially debilitating disease that has plagued
humanity for centuries and has claimed numerous lives across the globe. Concerted efforts …

Human tuberculosis (TB) is primarily caused by Mycobacterium tuberculosis (Mtb) that
inhabits inside and amidst immune cells of the host with adapted physiology to regulate …