Bacteria as Computers: Formalizing Transcriptional Regulatory Networks by Way of Digital Logic Circuits.

R Silva-Rocha, V de Lorenzo - International Journal of …, 2012 - search.ebscohost.com
Bacteria display a number of qualities that are typically associated to computers. These
include not only the distinct interplay between their hardware (ie their molecular machinery …

[HTML][HTML] Recognizing and engineering digital-like logic gates and switches in gene regulatory networks

RW Bradley, M Buck, B Wang - Current opinion in microbiology, 2016 - Elsevier
Highlights•Digital-like logic will underpin many future synthetic biology applications.•
Ultrasensitive responses mimic digital switching in analogue systems.•Control motifs such …

The Logic of Decision Making in Environmental Bacteria

R Silva‐Rocha, J Tamames… - … Processing: From Logic …, 2012 - Wiley Online Library
The regulatory and metabolic networks that rule biodegradation of pollutants by
environmental bacteria are wired to the rest of the cellular physiology through both …

Development of Bacteria‐Based Cellular Computing Circuits for Sensing and Control in Biological Systems

MA Teravest, Z Li, LT Angenent - … Information Processing: From …, 2012 - Wiley Online Library
Although the term “biocomputing” brings to mind biological replacements of silicon
processors, its application is not yet attainable. Use of bacteria‐based biocomputing for …

DEVELOPING A TRANSCRIPTIONAL PROGRAMMING EDIFICE USING SYSTEMS OF ENGINEERED TRANSCRIPTION FACTORS

RE Rondon - 2021 - repository.gatech.edu
The control of gene expression is an important tool for metabolic engineering, biomedicine,
and biomanufacturing. Currently, the field of Synthetic Biology is limited by the ability to …

[HTML][HTML] Mining logic gates in prokaryotic transcriptional regulation networks

R Silva-Rocha, V de Lorenzo - FEBS letters, 2008 - Elsevier
Prokaryotic transcriptional networks possess a large number of regulatory modules that
formally implement many of the logic gates that are typical of digital, Boolean circuits. Yet …

Biocircuit design through engineering bacterial logic gates

A Goni-Moreno, M Redondo-Nieto, F Arroyo… - Natural Computing, 2011 - Springer
Designing synthetic biocircuits to perform desired purposes is a scientific field that has
exponentially grown over the past decade. The advances in genome sequencing, bacteria …

[PDF][PDF] Biological Programmable Logic Device in Escherichia coli

M Sun - 2012 - central.bac-lac.gc.ca
Bio‐computing and Boolean logic gates simulation and implementation in bacteria and
eukaryotic cells is currently a hot subject in Synthetic Biology. Computer chips relies on …

Biology Through the Lens of Computer Science

N Forbes - 2005 - ieeexplore.ieee.org
Biology Through the Lens of Computer Science | part of Imitation of Life: How Biology Is
Inspiring Computing | MIT Press books | IEEE Xplore Biology Through the Lens of Computer …

Toward programmable biology

H Fellermann, O Markovitch, O Gilfellon… - ACS Synthetic …, 2016 - ACS Publications
This ACS Synthetic Biology special issue grew out of a focus workshop “Towards
Programmable Biology” which was held in York, UK, on July 20, 2015 as part of the …