[HTML][HTML] Transcriptomic and Genomic Approaches for Unravelling Candida albicans Biofilm Formation and Drug Resistance—An Update

PP Chong, VK Chin, WF Wong, P Madhavan, VC Yong… - Genes, 2018 - mdpi.com
Candida albicans is an opportunistic fungal pathogen, which causes a plethora of
superficial, as well as invasive, infections in humans. The ability of this fungus in switching …

[HTML][HTML] Candida pathogenesis: unravelling the threads of infection

BE Corner, PT Magee - Current Biology, 1997 - cell.com
Candida pathogenesis: Unravelling the threads of infection: Current Biology Skip to Main
Content Advertisement Current Biology This journal offers authors two options (open access or …

[HTML][HTML] From Jekyll to Hyde: The Yeast–Hyphal Transition of Candida albicans

EWL Chow, LM Pang, Y Wang - Pathogens, 2021 - mdpi.com
Candida albicans is a major fungal pathogen of humans, accounting for 15% of nosocomial
infections with an estimated attributable mortality of 47%. C. albicans is usually a benign …

Mapping of functional domains and characterization of the transcription factor Cph1 that mediate morphogenesis in Candida albicans

P Maiti, P Ghorai, S Ghosh, M Kamthan… - Fungal Genetics and …, 2015 - Elsevier
Cph1, a transcription factor of the Mitogen Activated Protein (MAP) kinase pathway,
regulates morphogenesis in human fungal pathogen Candida albicans. Here, by following a …

A 5′ UTR‐mediated translational efficiency mechanism inhibits the Candida albicans morphological transition

DS Childers, V Mundodi, M Banerjee… - Molecular …, 2014 - Wiley Online Library
While virulence properties of C andida albicans, the most commonly isolated human fungal
pathogen, are controlled by transcriptional and post‐translational mechanisms, considerably …

Distinct roles of Candida albicans-specific genes in host-pathogen interactions

D Wilson, FL Mayer, P Miramón, F Citiulo… - Eukaryotic …, 2014 - Am Soc Microbiol
Human fungal pathogens are distributed throughout their kingdom, suggesting that
pathogenic potential evolved independently. Candida albicans is the most virulent member …

BRG1 and NRG1 form a novel feedback circuit regulating Candida albicans hypha formation and virulence

IA Cleary, AL Lazzell, C Monteagudo… - Molecular …, 2012 - Wiley Online Library
In the opportunistic fungal pathogen Candida albicans both cellular morphology and the
capacity to cause disease are regulated by the transcriptional repressor Nrg1p. One of the …

[HTML][HTML] Candida albicans: A Major Fungal Pathogen of Humans

JP Richardson - Pathogens, 2022 - mdpi.com
Fungal infections kill~ 1.6 million people every year [1]. The fungal pathogen Candida
albicans causes> 150 million mucosal infections and~ 200,000 deaths per annum due to …

[PDF][PDF] Candida albicans: adapting to succeed

D Kadosh, JL Lopez-Ribot - Cell host & microbe, 2013 - cell.com
In this issue of Cell Host & Microbe, Lu et al.(2013) report on the redundancy of signaling
pathways controlling Candida albicans filamentation and pathogenicity. In the process, they …

[HTML][HTML] Dual-species transcriptional profiling during systemic candidiasis reveals organ-specific host-pathogen interactions

B Hebecker, S Vlaic, T Conrad, M Bauer, S Brunke… - Scientific reports, 2016 - nature.com
Candida albicans is a common cause of life-threatening fungal bloodstream infections. In
the murine model of systemic candidiasis, the kidney is the primary target organ while the …