Infection-Associated Genes of Candida Albicans

B Hube - Future microbiology, 2006 - Taylor & Francis
Advances in the medical treatment of life-threatening disorders have increased the
population of patients that are more susceptible to opportunistic microbial infections, such as …

[HTML][HTML] Dual-species transcriptional profiling during systemic candidiasis reveals organ-specific host-pathogen interactions

B Hebecker, S Vlaic, T Conrad, M Bauer, S Brunke… - Scientific reports, 2016 - nature.com
Candida albicans is a common cause of life-threatening fungal bloodstream infections. In
the murine model of systemic candidiasis, the kidney is the primary target organ while the …

Morphogenesis in Candida albicans

M Whiteway, C Bachewich - Annu. Rev. Microbiol., 2007 - annualreviews.org
Candida albicans is termed a dimorphic fungus because it proliferates in either a yeast form
or a hyphal form. The switch between these forms is the result of a complex interplay of …

Potential targets for antifungal drug discovery based on growth and virulence in Candida albicans

X Li, Y Hou, L Yue, S Liu, J Du… - Antimicrobial agents and …, 2015 - Am Soc Microbiol
Fungal infections, especially infections caused by Candida albicans, remain a challenging
problem in clinical settings. Despite the development of more-effective antifungal drugs, their …

Molecular Determinants Involved in Candida albicans Biofilm Formation and Regulation

D Kumar, A Kumar - Molecular Biotechnology, 2024 - Springer
Candida albicans is known for its pathogenicity, although it lives within the human body as a
commensal member. The commensal nature of C. albicans is well controlled and regulated …

Genome-Wide Transcriptional Profiling of the Cyclic AMP-Dependent Signaling Pathway during Morphogenic Transitions of Candida albicans

YS Bahn, M Molenda, JF Staab, CA Lyman… - Eukaryotic …, 2007 - Am Soc Microbiol
Candida albicans is an opportunistic human fungal pathogen that causes systemic
candidiasis as well as superficial mucosal candidiasis. In response to the host environment …

Coevolution of morphology and virulence in Candida species

DS Thompson, PL Carlisle, D Kadosh - Eukaryotic cell, 2011 - Am Soc Microbiol
Many of the major human fungal pathogens are known to undergo morphological changes,
which in certain cases are associated with virulence. Although there has been an intense …

Identifying infection-associated genes of Candida albicans in the postgenomic era

D Wilson, S Thewes, K Zakikhany, C Fradin… - FEMS yeast …, 2009 - academic.oup.com
The human pathogenic yeast Candida albicans can cause an unusually broad range of
infections reflecting a remarkable potential to adapt to various microniches within the human …

Expression levels of a filament-specific transcriptional regulator are sufficient to determine Candida albicans morphology and virulence

PL Carlisle, M Banerjee, A Lazzell… - Proceedings of the …, 2009 - National Acad Sciences
Candida albicans, the major human fungal pathogen, undergoes a reversible morphological
transition from single yeast cells to pseudohyphal and hyphal filaments (elongated cells …

[HTML][HTML] Recent advances in understanding Candida albicans hyphal growth

RA Arkowitz, M Bassilana - F1000Research, 2019 - ncbi.nlm.nih.gov
Morphological changes are critical for the virulence of a range of plant and human fungal
pathogens. Candida albicans is a major human fungal pathogen whose ability to switch …