Expression levels of a filament-specific transcriptional regulator are sufficient to determine Candida albicans morphology and virulence
PL Carlisle, M Banerjee, A Lazzell… - Proceedings of the …, 2009 - National Acad Sciences
Candida albicans, the major human fungal pathogen, undergoes a reversible morphological
transition from single yeast cells to pseudohyphal and hyphal filaments (elongated cells …
transition from single yeast cells to pseudohyphal and hyphal filaments (elongated cells …
Large-scale gene function analysis in Candida albicans
VM Bruno, AP Mitchell - Trends in Microbiology, 2004 - cell.com
Candida albicans is the most frequently isolated systemic fungal pathogen of humans.
Studies of gene function in C. albicans have relied heavily on budding yeast …
Studies of gene function in C. albicans have relied heavily on budding yeast …
Growth of Candida albicans hyphae
PE Sudbery - Nature Reviews Microbiology, 2011 - nature.com
The fungus Candida albicans is often a benign member of the mucosal flora; however, it
commonly causes mucosal disease with substantial morbidity and in vulnerable patients it …
commonly causes mucosal disease with substantial morbidity and in vulnerable patients it …
Promoter regulation in Candida albicans and related species
SE Eckert, FA Mühlschlegel - FEMS yeast research, 2009 - academic.oup.com
Regulation of gene expression has been studied extensively in Saccharomyces cerevisiae
and Schizosaccharomyces pombe. Some, but by far not all, of the findings are also …
and Schizosaccharomyces pombe. Some, but by far not all, of the findings are also …
Regulatory circuitry governing fungal development, drug resistance, and disease
Pathogenic fungi have become a leading cause of human mortality due to the increasing
frequency of fungal infections in immunocompromised populations and the limited …
frequency of fungal infections in immunocompromised populations and the limited …
Regulatory Circuits That Enable Proliferation of the Fungus Candida albicans in a Mammalian Host
JC Perez, AD Johnson - PLoS Pathogens, 2013 - journals.plos.org
The human body harbors trillions of microorganisms—a rich and diverse microbiota that
plays key roles in human health and disease. All three domains of life—eukaryotes …
plays key roles in human health and disease. All three domains of life—eukaryotes …
Transcriptional Response of Candida albicans upon Internalization by Macrophages
MC Lorenz, JA Bender, GR Fink - Eukaryotic cell, 2004 - Am Soc Microbiol
The opportunistic fungal pathogen Candida albicans is both a benign gut commensal and a
frequently fatal systemic pathogen. The interaction of C. albicans with the host's innate …
frequently fatal systemic pathogen. The interaction of C. albicans with the host's innate …
Functional genomic analysis of Candida albicans protein kinases reveals modulators of morphogenesis in diverse environments
Candida albicans is a leading cause of mycotic infection. The ability to transition between
yeast and filamentous forms is critical to C. albicans virulence and complex signaling …
yeast and filamentous forms is critical to C. albicans virulence and complex signaling …
Functional dichotomy for a hyphal repressor in Candida albicans
Y Mao, NV Solis, SG Filler, AP Mitchell - Mbio, 2023 - Am Soc Microbiol
Nrg1 is a repressor of hypha formation and hypha-associated gene expression in the fungal
pathogen Candida albicans. It has been well studied in the genetic background of the type …
pathogen Candida albicans. It has been well studied in the genetic background of the type …
Pathogenesis and virulence of Candida albicans
JP Lopes, MS Lionakis - Virulence, 2022 - Taylor & Francis
Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …