Despite the enormous progress made in terms of prevention and early intervention, a
pressing need remains to develop innovative therapeutic strategies for ischemic …

Despite major advances in medical, catheter-based or surgical treatment, cardiovascular
diseases such as peripheral artery disease and coronary artery disease still cause …

Therapeutic angiogenesis improves tissue ischemia by supplementing and supporting the
intrinsic process of angiogenesis. Besides direct administration of angiogenic growth factor …

There is widespread interest in the use of the angiogenic cytokine, vascular endothelial
growth factor (VEGF), for the treatment of cardiovascular disease. The main paradigm for …

Since the discovery of vascular endothelial growth factor (VEGF), therapeutic angiogenesis
has attracted interest as an alternative treatment for ischaemic heart and peripheral disease …

Left, Functional vascularization of an ischemic myocardial region requires both capillary
angiogenesis and coronary arteriogenesis (including the growth of preexisting collaterals) …

Members of the vascular endothelial growth factor (VEGF) family are among the most
powerful modulators of vascular biology. They regulate vasculogenesis, angiogenesis, and …

Therapeutic angiogenesis, that is, the generation of new vessels by delivery of specific
factors, is required both for rapid vascularization of tissue-engineered constructs and to treat …

Therapeutic over-expression of vascular endothelial growth factor (VEGF) can be used to
treat ischemic conditions. However, VEGF can induce either normal or aberrant …

Stimulation of angiogenesis, arteriogenesis, and lymphangiogenesis (ie, therapeutic
vascular growth) is a new concept for the treatment of ischemic cardiovascular diseases. A …