Mitochondria are central to cell function. The placenta forms the interface between maternal
and fetal systems, and placental mitochondria have critical roles in maintaining pregnancy …

The aetiology of many gestational disorders is still unknown. However, insufficient trans-
placental nutrient and oxygen transfer due to abnormal placentation is characteristic of …

Both obesity and gestational diabetes mellitus (GDM) lead to poor maternal and fetal
outcomes, including pregnancy complications, fetal growth issues, stillbirth, and …

Poor environmental conditions, including malnutrition, hypoxia and obesity in the mother
increase the risk of pregnancy complications, such as pre-eclampsia and gestational …

Preeclampsia is a devastating pregnancy disorder. Severity varies widely, and while severe
preeclampsia often requires pre-term delivery, women with mild preeclampsia may reach …

Key points Mitochondrial dysfunction is known to occur in diabetic phenotypes including
type 1 and 2 diabetes mellitus. The incidence of gestational diabetes mellitus (GDM) is …

Hypoxia is a common and severe stress to an organism's homeostatic mechanisms, and
hypoxia during gestation is associated with significantly increased incidence of maternal …

Introduction Placental mitochondria are subjected to micro-environmental changes
throughout gestation, in particular large variations in oxygen. How placental mitochondrial …

Abstract Purpose of Review Preeclampsia complicates 5–10% of all pregnancies and is a
leading cause of maternal and perinatal mortality and morbidity. The placenta plays a pivotal …

Abstract Preeclampsia complicates 5–8% of all pregnancies worldwide, and although its
pathophysiology remains obscure, placental oxidative stress and mitochondrial …