Preeclampsia is a pregnancy-specific syndrome with multisystem involvement which leads
to foetal, neonatal, and maternal morbidity and mortality. This syndrome is characterized by …

Low birth weight is associated with an increased risk for developing type 2 diabetes and
metabolic diseases. The placental capacity to supply nutrients and oxygen to the fetus …

When maintaining first trimester placental villi in organ culture under conventional normoxic
conditions, we have observed widespread degeneration of the syncytiotrophoblast within 24 …

In pregnancy fetal growth and development occur in a sexually dimorphic manner. Male and
female fetuses respond differently to the intrauterine environment with males …

Preeclampsia (PE) is a pregnancy complication that is diagnosed by the new onset of
hypertension and proteinuria. The etiology of PE remains unclear; however, growing …

Pregnancy is a state of oxidative stress arising from increased placental mitochondrial
activity and production of reactive oxygen species (ROS), mainly superoxide anion. The …

This review examines the place of mitochondria in the life cycle through oogenesis,
ovulation and early embryogenesis. Mitochondria are semi-autonomous organelles …

Mitochondria are in a constant balance of fusing and dividing in response to cellular cues.
Fusion creates healthy mitochondria, whereas fission results in removal of non-functional …

Introduction Intrauterine growth restriction (IUGR) and preeclampsia (PE) are pregnancy
disorders characterized by placental insufficiency with oxygen/nutrient restriction and …

Polycystic ovary syndrome (PCOS) is a complex, but relatively common endocrine disorder
associated with chronic anovulation, hyperandrogenism, and micro-polycystic ovaries. In …