The oocyte is recognised as the largest cell in mammalian species and other multicellular
organisms. Mitochondria represent a high proportion of the cytoplasm in oocytes and …

Mitochondria have long been known to be the powerhouses of the cell but they also
contribute to redox and Ca 2+ homeostasis, provide intermediary metabolites and store …

Development of the human placenta takes place in contrasting oxygen concentrations at
different stages of gestation, from~ 20 mmHg during the first trimester rising to~ 60 mmHg at …

In brief Placental oxidative stress contributes to both normal and abnormal placentation
during pregnancy. This review discusses the potential consequence of oxidative stress …

As the vital organelles for cell energy metabolism, mitochondria are essential for oocyte
maturation, fertilization, and embryo development. Abnormalities in quantity, quality, and …

During pregnancy, the placenta is a site of active oxygen metabolism that continuously
generates oxidative stress (OS). Overproduction of reactive oxygen species and reactive …