[HTML][HTML] Gemtuzumab ozogamicin, citosine arabinoside, G-CSF combination (G-AraMy) in the treatment of elderly patients with poor-prognosis acute myeloid …

L Fianchi, L Pagano, F Leoni, S Storti, MT Voso… - Annals of …, 2008 - Elsevier
Background Gemtuzumab ozogamicin (GO) is effective as single agent in the treatment of
acute myeloid leukemia (AML). We evaluated efficacy and safety of a chemotherapy …

High response rate for treatment with gemtuzumab ozogamicin and cytarabine in elderly patients with acute myeloid leukemia and favorable and intermediate-I …

S Tavor, E Rahamim, N Sarid, U Rozovski… - … Myeloma and Leukemia, 2012 - Elsevier
Background The benefit of gemtuzumab ozogamicin (GO) in combination with
chemotherapy as frontline therapy in patients with acute myeloid leukemia (AML) is still …

Gemtuzumab ozogamicin as first‐line treatment in patients aged 70 years or older with acute myeloid leukemia

W McHayleh, K Foon, R Redner, R Sehgal, A Raptis… - Cancer, 2010 - Wiley Online Library
BACKGROUND: Elderly patients with acute myeloid leukemia (AML) are generally unable to
withstand the rigors of intensive induction chemotherapy and its attendant complications …

Gemtuzumab ozogamicin in combination with attenuated doses of standard induction chemotherapy can successfully induce complete remission without increasing …

KS Eom, HJ Kim, WS Min, S Lee, CK Min… - European journal of …, 2007 - Wiley Online Library
Background: In this study, the effectiveness and safety of combining gemtuzumab
ozogamicin (GO) with an abbreviated schedule of standard induction chemotherapy were …

Sequential combination of gemtuzumab ozogamicin and standard chemotherapy in older patients with newly diagnosed acute myeloid leukemia: results of a …

S Amadori, S Suciu, R Stasi, HR Salih… - Journal of clinical …, 2013 - ascopubs.org
Purpose This randomized trial evaluated the efficacy and toxicity of sequential gemtuzumab
ozogamicin (GO) and standard chemotherapy in older patients with newly diagnosed acute …

[PDF][PDF] Sequential administration of gemtuzumab ozogamicin and conventional chemotherapy as first line therapy in elderly patients with acute myeloid leukemia: a …

S Amadori, S Suciu, R Willemze, F Mandelli… - 2004 - repository.ubn.ru.nl
BACKGROUND AND OBJECTIVES: Acute myeloid leukemia (AML) in the elderly is
associated with low rates of response to conventional chemotherapy and long-term survival …

First experience with gemtuzumab ozogamicin plus cytarabine as continuous infusion for elderly acute myeloid leukaemia patients

PP Piccaluga, G Martinelli, M Rondoni, M Malagola… - Leukemia research, 2004 - Elsevier
Gemtuzumab ozogamicin (GO), an anti-CD33 monoclonal antibody conjugated to
calicheamicin, is effective as single agent in the treatment of poor risk acute myeloid …

Gemtuzumab ozogamicin (mylotarg) for the treatment of acute myeloid leukemia–ongoing trials

B Gleissner, R Schlenk, M Bornhäuser… - Oncology Research and …, 2007 - karger.com
The value of the combination of gemtuzumab ozogamicin (GO) and chemotherapy for the
treatment of acute myeloid leukemia (AML) is currently analyzed within clinical trials. GO (6 …

Phase II pilot trial of gemtuzumab ozogamicin (GO) as first line therapy in acute myeloid leukemia patients age 65 or older

C Nabhan, LM Rundhaugen, MB Riley, A Rademaker… - Leukemia research, 2005 - Elsevier
The prognosis of acute myeloid leukemia (AML) in older adults is generally poor. Standard
cytotoxic chemotherapy is usually poorly tolerated and provides dismal results in this patient …

Addition of gemtuzumab ozogamicin to induction chemotherapy improves survival in older patients with acute myeloid leukemia

AK Burnett, NH Russell, RK Hills, J Kell… - Journal of clinical …, 2012 - ascopubs.org
Purpose There has been little survival improvement in older patients with acute myeloid
leukemia (AML) in the last two decades. Improving induction treatment may improve the rate …