Amiodarone-induced severe hepatitis mediated by immunological mechanisms.
HW Breuer, W Bossek, C Haferland… - … journal of clinical …, 1998 - europepmc.org
A 64-year-old man developed a fulminant hepatitis 4 days after initiation of amiodarone
treatment and a total dose of 7.1 g. The direct Coombs test was positive and became …
treatment and a total dose of 7.1 g. The direct Coombs test was positive and became …
Toxicity of amiodarone and amiodarone analogues on isolated rat liver mitochondria
M Spaniol, R Bracher, HR Ha, F Follath… - Journal of …, 2001 - Elsevier
Background: Amiodarone is a well-known mitochondrial toxin consisting of a benzofuran
ring (ring A) coupled to a p-OH-benzene structure substituted with 2 iodines and a diethyl …
ring (ring A) coupled to a p-OH-benzene structure substituted with 2 iodines and a diethyl …
Causality assessment of liver injury after chronic oral amiodarone intake
L Llanos, R Moreu, AM Peiró, S Pascual… - … and Drug Safety, 2009 - Wiley Online Library
Abstract Background/Aim The number of patients receiving amiodarone will increase in
future years. As clinically significant hepatotoxicity associated with oral amiodarone is …
future years. As clinically significant hepatotoxicity associated with oral amiodarone is …
Granular cells as a marker of early amiodarone hepatotoxicity: a pathological and analytical study.
NA Shepherd, AM Dawson, PR Crocker… - Journal of clinical …, 1987 - jcp.bmj.com
Two contrasting cases of amiodarone hepatotoxicity are described. In one, perivenular
collections of swollen cells, probably macrophages, with granular cytoplasm in an otherwise …
collections of swollen cells, probably macrophages, with granular cytoplasm in an otherwise …
Frequent neurologic toxicity associated with amiodarone therapy
ME Charness, F Morady, MM Scheinman - Neurology, 1984 - AAN Enterprises
Fifty-four consecutive patients were treated with amiodarone for symptomatic ventricular
tachycardia or ventricular fibrillation refractory to treatment with conventional antiarrhythmic …
tachycardia or ventricular fibrillation refractory to treatment with conventional antiarrhythmic …
Severe ataxia caused by amiodarone
DG Krauser, AZ Segal, P Kligfield - The American journal of cardiology, 2005 - Elsevier
Neurologic toxicity is an infrequently reported and under-recognized consequence of
amiodarone, symptoms of which may include tremor, peripheralsensorimotor neuropathy …
amiodarone, symptoms of which may include tremor, peripheralsensorimotor neuropathy …
[HTML][HTML] Acute hepatitis after amiodarone infusion
P Fonseca, A Dias, H Gonçalves… - World Journal of …, 2015 - ncbi.nlm.nih.gov
Acute hepatitis is a very rare, but potentially fatal, adverse effect of intravenous amiodarone.
We present a case of an 88-year-old man with history of ischemic dilated cardiomyopathy …
We present a case of an 88-year-old man with history of ischemic dilated cardiomyopathy …
Acute overdosage of amiodarone in a suicide attempt
M Bonati, V D'aranno, F Galletti… - Journal of Toxicology …, 1983 - Taylor & Francis
Clinical and biochemical variables and blood levels of amiodarone and its metabolite are
reported after acute self-intoxication in a young woman. Despite the huge amount of drug …
reported after acute self-intoxication in a young woman. Despite the huge amount of drug …
Acute hepatitis following amiodarone administration
E Tagliamonte, G Cice, V Ducceschi… - Minerva …, 1997 - europepmc.org
A 61 year old man, treated with amiodarone since 1993 for resistant supraventricular
arrhythmias, developed acute hepatitis after an intravenous amiodarone administration …
arrhythmias, developed acute hepatitis after an intravenous amiodarone administration …
[HTML][HTML] N-acetylcysteine treats intravenous amiodarone induced liver injury
ML Mudalel, KP Dave, JP Hummel… - World Journal of …, 2015 - ncbi.nlm.nih.gov
We report a case of intravenous (IV) amiodarone drug induced liver injury (DILI). The patient
received IV N-acetylcysteine (NAC) which resulted in a rapid improvement in liver enzymes …
received IV N-acetylcysteine (NAC) which resulted in a rapid improvement in liver enzymes …