The best characterized pilus of Vibrio cholerae is the toxin‐coregulated pilus (TCP)
described by Taylor and coworkers. The pilus is designated TCP, for toxin‐coregulated …

Gram-negative bacteria use type II secretion systems for the transport of virulence factors
and hydrolytic enzymes through the outer membrane. These sophisticated multi-protein …

Type IV pili are long thin surface-displayed polymers of the pilin subunit that are present in a
diverse group of bacteria. These multifunctional filaments are critical to virulence for …

The pseudopilus is a key feature of the type 2 secretion system (T2SS) and is made up of
multiple pseudopilins that are similar in fold to the type 4 pilins. However, pilins have …

The type II secretion system (T2SS) is used by several Gram-negative bacteria for the
secretion of hydrolytic enzymes and virulence factors across the outer membrane. In these …

Secretion of cholera toxin and other virulence factors from Vibrio cholerae is mediated by the
type II secretion (T2S) apparatus, a multiprotein complex composed of both inner and outer …

The toxin-coregulated pilus (TCP) of Vibrio cholerae and the soluble TcpF protein that is
secreted via the TCP biogenesis apparatus are essential for intestinal colonization. The TCP …

The toxin-co-regulated pilus (TCP), an important colonization factor of Vibrio cholerae, is
similar to the type 4 pilus produced by a variety of pathogenic Gram-negative bacteria. The …

Biogenesis of the toxin-coregulated pilus (TCP) of Vibrio cholerae 01 is essential for
successful bacterial colonization of the small intestine. Pilus assembly requires the products …

Biogenesis of the Vibrio cholerae toxin-coregulated pilus (TCP) requires the activities of at
least seven accessory proteins. We demonstrate that a portion of this pathway involves a …