The general secretion pathway (GSP), found in a wide range of bacteria, is responsible for
extracellular targeting of a subset of proteins from the periplasm. In Pseudomonas …

Defined chromosomal mutations that lead to assembly failure of the toxin coregulated pilus
(TCP) of Vibrio cholerae provide useful insights into the biogenesis of a type-4 pilus. Mutants …

The secreton (type II secretion) and type IV pilus biogenesis branches of the general
secretory pathway in Gram‐negative bacteria share many features that suggest a common …

Type IV pili are cell surface organelles found on many Gram-negative bacteria. They
mediate a variety of functions, including adhesion, twitching motility, and competence for …

The highly conserved pilM/N/O/P/Q gene cluster is among the core set of genes required for
cell surface expression of type IV pili and associated twitching motility. With the exception of …

Pilus biogenesis on the surface of uropathogenic Escherichia coli requires the
chaperone/usher pathway, a terminal branch of the general secretory pathway. In this …

Colonization of the host intestine is the most important step in Vibrio cholerae infection. The
toxin-coregulated pilus (TCP), an operon-encoded type IVb pilus (T4bP), plays a crucial role …

ABSTRACT Type IV pili (T4P) are filamentous surface appendages required for tissue
adherence, motility, aggregation, and transformation in a wide array of bacteria and …

Production of type IV bundle-forming pili (BFP) by enteropathogenic Escherichia coli (EPEC)
requires the protein products of 12 genes of the 14-gene bfp operon. Antisera against each …

The toxin-coregulated pilus (TCP) of Vibrio cholerae is a type 4-related fimbrial adhesin and
a useful model for the study of type 4 pilus biogenesis and related bacterial macromolecular …