In Vibrio cholerae, elaboration of toxin-coregulated pilus and protein secretion by the
extracellular protein secretion apparatus occurred in the absence of both TonB systems. In …

Type IV pili (T4Ps) are long cell surface filaments, essential for microcolony formation, tissue
adherence, motility, transformation, and virulence by human pathogens. The …

Pseudomonas aeruginosa utilizes the type II secretion machinery to transport virulence
factors through the outer membrane into the extracellular space. Five proteins in the type II …

The PapC usher is an outer membrane protein required for assembly and secretion of P pili
in uropathogenic Escherichia coli. P pilus biogenesis occurs by the chaperone/usher …

Several experimental approaches have provided evidence suggesting that a domain within
the C-terminal region of the TcpA pilin, delineated by the single disulfide loop, is directly …

The type II secretion machinery allows most Gram‐negative bacteria to deliver virulence
factors into their surroundings. We report that in Erwinia chrysanthemi, GspE (the putative …

The Vibrio cholerae toxin co-regulated pilus (TCP) is a type 4b pilus that mediates bacterial
microcolony formation, which is essential for intestinal colonization. Structural analyses have …

The process of extracellular secretion in Pseudomonas aeruginosa requires specialized
machinery which is widely distributed among bacteria that actively secrete proteins to the …

Summary Type IVa pili (T4aP) function as bacterial virulence factors. T4aP pass through the
outer membranes of Gram-negative bacteria via homo-oligomeric secretins. We present a …

The Type 2 Secretion System (T2SS), occurring in many Gram-negative bacteria, is
responsible for the transport of a diversity of proteins from the periplasm across the outer …