Logical modeling of dendritic cells in vitro differentiation from human monocytes unravels novel transcriptional regulatory interactions

KJ Nuñez-Reza, A Naldi, A Sanchéz-Jiménez… - bioRxiv, 2020 - biorxiv.org
Dendritic cells are the major specialized antigen-presenting cells, thereby connecting innate
and adaptive immunity. Because of their role in establishing adaptive immunity, they have …

Logical modelling of in vitro differentiation of human monocytes into dendritic cells unravels novel transcriptional regulatory interactions

KJ Nuñez-Reza, A Naldi… - Interface …, 2021 - royalsocietypublishing.org
Dendritic cells (DCs) are the major specialized antigen-presenting cells, thereby connecting
innate and adaptive immunity. Because of their role in establishing adaptive immunity, they …

Transcriptional regulation of dendritic cell development and function

S Zhang, C Audiger, M Chopin, SL Nutt - Frontiers in immunology, 2023 - frontiersin.org
Dendritic cells (DCs) are sentinel immune cells that form a critical bridge linking the innate
and adaptive immune systems. Extensive research addressing the cellular origin and …

[图书][B] Checks and Balances: Transcriptional Regulation of Myeloid Innate Immunity and Dendritic Cell Maturation

R Nazitto - 2021 - search.proquest.com
Antigen presenting cells such as myeloid dendritic cells (DCs) are key sentinels of the innate
immune system. In response to pathogen recognition and innate immune stimulation, DCs …

ILF3 is a negative transcriptional regulator of innate immune responses and myeloid dendritic cell maturation

R Nazitto, LM Amon, FD Mast, JD Aitchison… - The Journal of …, 2021 - journals.aai.org
APCs such as myeloid dendritic cells (DCs) are key sentinels of the innate immune system.
In response to pathogen recognition and innate immune stimulation, DCs transition from an …

Dendritic cell lineage commitment is instructed by distinct cytokine signals

KM Seré, Q Lin, P Felker, N Rehage, T Klisch… - European journal of cell …, 2012 - Elsevier
Dendritic cells (DC) develop from hematopoietic stem cells, which is guided by instructive
signals through cytokines. DC development progresses from multipotent progenitors (MPP) …

Mechanisms regulating dendritic cell specification and development

SS Watowich, YJ Liu - Immunological reviews, 2010 - Wiley Online Library
Understanding the diversification of dendritic cell (DC) lineages is one of the last frontiers in
mapping the developmental hierarchy of the hematopoietic system. DCs are a vital link …

Genome-wide analysis of dendritic cell differentiation

I Tiniakou, PF Hsu, LS Lopez-Zepeda, CM Lau, C Soni… - bioRxiv, 2022 - biorxiv.org
Dendritic cells (DCs) are immune sentinel cells that comprise antigen-presenting
conventional DCs (cDCs) and cytokine-producing plasmacytoid DCs (pDCs). Cytokine Flt3 …

Plasticity in the transcriptional and epigenetic circuits regulating dendritic cell lineage specification and function

F Paul, I Amit - Current Opinion in Immunology, 2014 - Elsevier
Dendritic cells (DC) are critical and functionally versatile innate immune sentinels. Here, we
coarsely partition the adult DC lineage into three developmental subtypes and argue that …

IFN regulatory factor-4 and-8 govern dendritic cell subset development and their functional diversity

T Tamura, P Tailor, K Yamaoka, HJ Kong… - The Journal of …, 2005 - journals.aai.org
Dendritic cells (DCs) are bone marrow (BM)-derived APCs central to both innate and
adaptive immunity. DCs are a heterogeneous cell population composed of multiple subsets …