5-HT1A/5-HT7 receptor interplay: Chronic activation of 5-HT7 receptors decreases the functional activity of 5-HT1A receptor and its сontent in the mouse brain
EM Kondaurova, DV Bazovkina, VS Naumenko - Molecular Biology, 2017 - Springer
Serotonin receptors 5-HT 1A and 5-HT 7 are involved in the development of various
psychopathologies. Some data indicate that there is an interplay between 5-HT 1A 5-HT 7 …
psychopathologies. Some data indicate that there is an interplay between 5-HT 1A 5-HT 7 …
Human 5-HT5 receptors: the 5-HT5A receptor is functional but the 5-HT5B receptor was lost during mammalian evolution
We have isolated from a human genomic library the human 5-hydroxytryptamine 5-HT5A
and 5-HT5B genes. The human 5-HT5A gene encodes a protein with similar characteristics …
and 5-HT5B genes. The human 5-HT5A gene encodes a protein with similar characteristics …
5-HT1A receptor as a key player in the brain 5-HT system
NK Popova, VS Naumenko - Reviews in the Neurosciences, 2013 - degruyter.com
Among an impressive variety of identified serotonin receptors, 5-HT 1A attracts particular
attention due to its central role in the regulation of 5-HT-ergic neurotransmission and the …
attention due to its central role in the regulation of 5-HT-ergic neurotransmission and the …
Cloning, expression and pharmacology of the mouse 5-HT4L receptor
S Claeysen, M Sebben, L Journot, J Bockaert… - Febs Letters, 1996 - Elsevier
Since most of our knowledge on pharmacological properties of brain 5-HT4 receptors have
been discussed for mouse colliculi neurons, we cloned the corresponding receptor using the …
been discussed for mouse colliculi neurons, we cloned the corresponding receptor using the …
Developmental expression of 5-HT5A receptor mRNA in the rat brain
G García-Alcocer, G Sarabia-Altamirano… - Neuroscience …, 2005 - Elsevier
In the central nervous system, serotonin (5-HT) may function as a mitogen as well as a
neurotransmitter; and its early appearance suggests a potential role in development. The …
neurotransmitter; and its early appearance suggests a potential role in development. The …
Serotonin 5‐HT7 receptor overexpression in the raphe nuclei area produces antidepressive effect and affects brain serotonin system in male mice
AY Rodnyy, EM Kondaurova… - Journal of …, 2022 - Wiley Online Library
Abstract Heterodimerization between 5‐HT7 and 5‐HT1A receptors seems to play an
important role in the mechanism of depression and antidepressant drug action. It was …
important role in the mechanism of depression and antidepressant drug action. It was …
Identification of a human 5-HT6 receptor variant produced by alternative splicing
MA Olsen, SP Nawoschik, BR Schurman… - Molecular brain …, 1999 - Elsevier
The complexity of the 5-hydroxytryptamine (5-HT)(serotonin) receptor family has been
increased by the findings that isoforms or splice variants exist for subtypes such as the 5 …
increased by the findings that isoforms or splice variants exist for subtypes such as the 5 …
Identification of 5-HT3A and 5-HT3B receptor subunits in human hippocampus
CA Brady, TJ Dover, AN Massoura, AP Princivalle… - …, 2007 - Elsevier
The pentameric 5-HT3 receptor complex is a ligand-gated ion channel that mediates fast
synaptic transmission in the brain. Expression of two subunits (5-HT3A and 5-HT3B …
synaptic transmission in the brain. Expression of two subunits (5-HT3A and 5-HT3B …
Genomic responses to 5-HT1a or 5-HT2a2c receptor activation is differentially regulated in four regions of rat brain
N Tilakaratne, E Friedman - European journal of pharmacology, 1996 - Elsevier
The functional profiles of brain 5-HT1A and 5-HT2A c receptors were assessed by
quantitating changes in the immediate early genes—c-fos, ngflc and tisl, following receptor …
quantitating changes in the immediate early genes—c-fos, ngflc and tisl, following receptor …
The mouse 5HT5 receptor reveals a remarkable heterogeneity within the 5HT1D receptor family.
JL Plassat, U Boschert, N Amlaiky, R Hen - The EMBO journal, 1992 - embopress.org
Serotonin (5‐HT) is a neuromodulator that mediates a wide range of physiological functions
by activating multiple receptors. Using a strategy based on amino acid sequence homology …
by activating multiple receptors. Using a strategy based on amino acid sequence homology …