Molecular profiling in the age of cancer genomics
In this new era of cancer genomics, large-scale queries of whole genomic characteristics are
now possible not only for research and biological understanding, but also for molecular …
now possible not only for research and biological understanding, but also for molecular …
Genomics and proteomics: emerging technologies in clinical cancer research
Fueled by the complete genomic data acquired from the human genome project and the
desperate clinical need of comprehensive analytical tools to study a heterogeneous disease …
desperate clinical need of comprehensive analytical tools to study a heterogeneous disease …
Molecular profiling of cancer—the future of personalized cancer medicine: a primer on cancer biology and the tools necessary to bring molecular testing to the clinic
T Stricker, DVT Catenacci, TY Seiwert - Seminars in oncology, 2011 - Elsevier
Cancers arise as a result of an accumulation of genetic aberrations that are either acquired
or inborn. Virtually every cancer has its unique set of molecular changes. Technologies have …
or inborn. Virtually every cancer has its unique set of molecular changes. Technologies have …
Profiling the cancer genome
PA Cowin, M Anglesio… - Annual review of …, 2010 - annualreviews.org
Cancer profiling studies have had a profound impact on our understanding of the biology of
cancers in a number of ways, including providing insights into the biological heterogeneity of …
cancers in a number of ways, including providing insights into the biological heterogeneity of …
[引用][C] Genomic profiling of cancer: what next?
P Workman, PG Johnston - Journal of Clinical Oncology, 2005 - ascopubs.org
During the last decade, the development of a number of high-throughput genomic
technologies has begun to have significant implications for both clinical and basic research …
technologies has begun to have significant implications for both clinical and basic research …
[HTML][HTML] Translational genomics in cancer research: converting profiles into personalized cancer medicine
Cancer genomics is a rapidly growing discipline in which the genetic molecular basis of
malignancy is studied at the scale of whole genomes. While the discipline has been …
malignancy is studied at the scale of whole genomes. While the discipline has been …
Transcriptomics in cancer diagnostics: developments in technology, clinical research and commercialization
M Sager, NC Yeat, S Pajaro-Van der Stadt… - Expert Review of …, 2015 - Taylor & Francis
Transcriptomic technologies are evolving to diagnose cancer earlier and more accurately to
provide greater predictive and prognostic utility to oncologists and patients. Digital …
provide greater predictive and prognostic utility to oncologists and patients. Digital …
[图书][B] Fast Facts: Comprehensive Genomic Profiling: Making Precision Medicine Possible
BL Rapoport, G Troncone, F Schmitt, S Nayler - 2020 - books.google.com
Cancer is a multifaceted disease in which genetic changes induce uncontrolled tumor
growth. Genomic characterization of cancer is now leading to better diagnostic, prognostic …
growth. Genomic characterization of cancer is now leading to better diagnostic, prognostic …
Managing the genomic revolution in cancer diagnostics
D Nguyen, CD Gocke - Virchows Archiv, 2017 - Springer
Molecular tumor profiling is now a routine part of patient care, revealing targetable genomic
alterations and molecularly distinct tumor subtypes with therapeutic and prognostic …
alterations and molecularly distinct tumor subtypes with therapeutic and prognostic …
Comprehensive analysis of cancer-proteogenome to identify biomarkers for the early diagnosis and prognosis of cancer
HD Shukla - Proteomes, 2017 - mdpi.com
During the past century, our understanding of cancer diagnosis and treatment has been
based on a monogenic approach, and as a consequence our knowledge of the clinical …
based on a monogenic approach, and as a consequence our knowledge of the clinical …