The circadian rhythm is a nearly 24‐h oscillation found in various physiological processes in
the human brain and body that is regulated by environmental and genetic factors. It is …

Disturbance of the circadian system, manifested as disrupted daily rhythms of physiologic
parameters such as sleep, activity, and hormone secretion, has long been observed as a …

Endogenous biological clocks, orchestrated by the suprachiasmatic nucleus, time the
circadian rhythms that synchronize physiological and behavioural functions in humans. The …

The circadian clock controls daily rhythms in animal physiology, metabolism, and behavior,
such as the sleep‐wake cycle. Disruption of circadian rhythms has been revealed in many …

Circadian clocks, endogenous oscillators generating daily biological rhythms, have
important roles in the nervous system to control diverse cellular processes—not only in the …

Disruptions of circadian rhythms and sleep cycles are common among neurodegenerative
diseases and can occur at multiple levels. Accumulating evidence reveals a bidirectional …

Despite varied etiologies and symptoms, several neurodegenerative diseases—specifically,
Alzheimer's (AD), Parkinson's (PD), and Huntington's diseases (HDs)—share the common …

Circadian rhythms are recurring patterns in a host of physiological and other parameters that
recur with periods of near 24 h. These rhythms reflect the temporal organization of an …

Circadian rhythm dysfunction occurs in both common and rare neurodegenerative diseases.
This dysfunction manifests as sleep cycle mistiming, alterations in body temperature …

Ageing leads to a functional deterioration of many brain systems, including the circadian
clock—an internal time-keeping system that generates∼ 24-hour rhythms in physiology and …