Interleukin-33 (IL-33) is the 11th member of IL-1 cytokine family which includes IL-1 and IL-
18. Unlike IL-1β and IL-18, IL-33 is suggested to function as an alarmin that is released upon …

Background Interleukin-33 (IL-33) is a novel cytokine that triggers inflammatory immune
responses, but evidence of its role in human asthma, a common allergic airway disease, is …

Interleukin 33 (IL-33) is an alarmin cytokine from the IL-1 family. IL-33 is localized in the
nucleus and acts there as a gene regulator. Following injury, stress or cell death, it is …

Abstract IL-33 is an IL-1-related cytokine which has been implicated in Th2-associated
biology and allergic diseases in humans and mice. IL-33 stimulates Th2 cells, mast cells …

In complex disorders such as asthma and allergic disease, the goal for developing disease-
modifying biotherapeutics is to find a target that is a central instigator of immunologic activity …

Objective Identify key features of IL-33 immunobiology important in allergic and nonallergic
airway inflammatory diseases and potential therapeutic strategies to reduce disease burden …

IL− 33 was recently identified as an IL− 1 family member and the functional ligand of the
T1/ST2 receptor. T1/ST2 is an important regulator of Th2− type responses, which suggests …

Interleukin (IL)-33 is a recently described member of the IL-1 family and has been shown to
induce production of T helper type 2 cytokines. In this study, an anti-IL-33 antibody was …

Abstract Interleukin-33 (IL-33), a member of the IL-1 family, is an alarmin cytokine with
crucial roles in tissue homeostasis and repair, type 2 immunity, allergic and non-allergic …

Background Several animal studies, and one inoculation study in adult asthmatics have
shown that interleukin-33 (IL-33) is a major contributor to type-2 inflammation in acute …