Several studies have focused their attention on the relationship between host genetic factors
and susceptibility/resistance to severe malaria. However, there is a paucity of information …

Several human genetic factors, including red blood cell polymorphisms (ABO blood group,
sickle-cell trait, G6PD deficiency) as well as point mutations in the mannose binding protein …

Background The clinical presentation of malaria, considered as the result of a complex
interaction between parasite and human genetics, is described to be different between rural …

The multifactorial pathogenesis of severe malaria is partly attributed to host genes, such as
those encoding cytokines involved in complex inflammatory reactions, namely tumor …

Background Malaria is a major public health problem in Cameroon. The study of the genetic
diversity within parasite population is essential for understanding the mechanism underlying …

To investigate the effects of host polymorphisms on malaria morbidity and infection, the
frequency distributions of TNF α promotor gene and sickle cell trait were studied in infants in …

Background Plasmodium falciparum malaria is one of the most widespread and deadliest
infectious diseases in children under five years in endemic areas. The disease has been a …

Introduction: molecular characterization of malaria parasites from different localities is
important to improve understanding of acquisition of natural immunity to Plasmodium …

Multiple factors are involved in the variability of host's response to P. falciparum infection,
like the intensity and seasonality of malaria transmission, the virulence of parasite and host …

We have investigated the association between alleles of the genes for tumour necrosis
factor-alpha (TNF-α) and TNF-β and severity of disease during malarial (Plasmodium …