Systemic inflammation and the brain: novel roles of genetic, molecular, and environmental cues as drivers of neurodegeneration
R Sankowski, S Mader… - Frontiers in cellular …, 2015 - frontiersin.org
The nervous and immune systems have evolved in parallel from the early bilaterians, in
which innate immunity and a central nervous system (CNS) coexisted for the first time, to …
which innate immunity and a central nervous system (CNS) coexisted for the first time, to …
The brain as a target for inflammatory processes and neuroprotective strategies
SD Skaper - Annals of the New York Academy of Sciences, 2007 - Wiley Online Library
The importance of glial cell–propagated inflammation (ie, neuroinflammation) disorders
such as Alzheimer's disease (AD) was viewed previously as a bystander effect, or …
such as Alzheimer's disease (AD) was viewed previously as a bystander effect, or …
An inflammation-centric view of neurological disease: beyond the neuron
Inflammation is a complex biological response fundamental to how the body deals with
injury and infection to eliminate the initial cause of cell injury and effect repair. Unlike a …
injury and infection to eliminate the initial cause of cell injury and effect repair. Unlike a …
Current perspectives on the link between neuroinflammation and neurogenesis
The link between neuroinflammation and neurogenesis is an area of intensive research in
contemporary neuroscience. The burgeoning amount of evidence accumulated over the …
contemporary neuroscience. The burgeoning amount of evidence accumulated over the …
The brain as a target of inflammation: common pathways link inflammatory and neurodegenerative diseases
F Zipp, O Aktas - Trends in neurosciences, 2006 - cell.com
Classical knowledge distinguishes between inflammatory and non-inflammatory diseases of
the brain. Either the immune system acts on the CNS and initiates a damage cascade, as in …
the brain. Either the immune system acts on the CNS and initiates a damage cascade, as in …
The role of the innate immune system in psychiatric disorders
KA Jones, C Thomsen - Molecular and Cellular Neuroscience, 2013 - Elsevier
There is by now substantial clinical evidence for an association between specific mood
disorders and altered immune function. More recently, a number of hypotheses have been …
disorders and altered immune function. More recently, a number of hypotheses have been …
[HTML][HTML] Neuroinflammation: ways in which the immune system affects the brain
RM Ransohoff, D Schafer, A Vincent, NE Blachère… - …, 2015 - Elsevier
Neuroinflammation is the response of the central nervous system (CNS) to disturbed
homeostasis and typifies all neurological diseases. The main reactive components of the …
homeostasis and typifies all neurological diseases. The main reactive components of the …
Inflammation mediates varying effects in neurogenesis: relevance to the pathogenesis of brain injury and neurodegenerative disorders
Brain inflammation is a complex cellular and molecular response to stress, injury or infection
of the CNS in attempt to defend against insults, clear dead and damaged neurons and return …
of the CNS in attempt to defend against insults, clear dead and damaged neurons and return …
Recent advances in the mechanisms of neuroinflammation and their roles in neurodegeneration
R Niranjan - Neurochemistry international, 2018 - Elsevier
Neuroinflammation is associated with the pathogenesis of many neurological disorders
including Parkinson's disease, Alzheimer's disease, Amyotrophic lateral sclerosis and …
including Parkinson's disease, Alzheimer's disease, Amyotrophic lateral sclerosis and …
Inflammation in CNS neurodegenerative diseases
J Stephenson, E Nutma, P van der Valk, S Amor - Immunology, 2018 - Wiley Online Library
Neurodegenerative diseases, the leading cause of morbidity and disability, are gaining
increased attention as they impose a considerable socioeconomic impact, due in part to the …
increased attention as they impose a considerable socioeconomic impact, due in part to the …