A review of using mathematical modeling to improve our understanding of bacteriophage, bacteria, and eukaryotic interactions
Phage therapy, the therapeutic usage of viruses to treat bacterial infections, has many
theoretical benefits in the 'post antibiotic era.'Nevertheless, there are currently no approved …
theoretical benefits in the 'post antibiotic era.'Nevertheless, there are currently no approved …
Modeling bacteria–phage interactions and its implications for phage therapy
Bacteriophages are more abundant than any other organism on our planet. The interaction
of bacteriophages and bacteria and their coevolution is well known. In this chapter, we …
of bacteriophages and bacteria and their coevolution is well known. In this chapter, we …
Computational approaches to predict bacteriophage–host relationships
Metagenomics has changed the face of virus discovery by enabling the accurate
identification of viral genome sequences without requiring isolation of the viruses. As a …
identification of viral genome sequences without requiring isolation of the viruses. As a …
Quantitative Models of In Vitro Bacteriophage–Host Dynamics and Their Application to Phage Therapy
Phage therapy is the use of bacteriophages as antimicrobial agents for the control of
pathogenic and other problem bacteria. It has previously been argued that successful …
pathogenic and other problem bacteria. It has previously been argued that successful …
Population and evolutionary dynamics of phage therapy
Following a sixty-year hiatus in western medicine, bacteriophages (phages) are again being
advocated for treating and preventing bacterial infections. Are attempts to use phages for …
advocated for treating and preventing bacterial infections. Are attempts to use phages for …
Combination of in vivo phage therapy data with in silico model highlights key parameters for pneumonia treatment efficacy
R Delattre, J Seurat, F Haddad, TT Nguyen… - Cell Reports, 2022 - cell.com
The clinical (re) development of bacteriophage (phage) therapy to treat antibiotic-resistant
infections faces the challenge of understanding the dynamics of phage-bacteria interactions …
infections faces the challenge of understanding the dynamics of phage-bacteria interactions …
Systematic analysis of putative phage-phage interactions on minimum-sized phage cocktails
F Molina, M Menor-Flores, L Fernández… - Scientific Reports, 2022 - nature.com
The application of bacteriophages as antibacterial agents has many benefits in the “post-
antibiotic age”. To increase the number of successfully targeted bacterial strains, phage …
antibiotic age”. To increase the number of successfully targeted bacterial strains, phage …
Promises and pitfalls of in vivo evolution to improve phage therapy
Phage therapy is the use of bacterial viruses (phages) to treat bacterial infections, a medical
intervention long abandoned in the West but now experiencing a revival. Currently …
intervention long abandoned in the West but now experiencing a revival. Currently …
Black box of phage–bacterium interactions: Exploring alternative phage infection strategies
S Mäntynen, E Laanto, HM Oksanen… - Open …, 2021 - royalsocietypublishing.org
The canonical lytic–lysogenic binary has been challenged in recent years, as more
evidence has emerged on alternative bacteriophage infection strategies. These infection …
evidence has emerged on alternative bacteriophage infection strategies. These infection …
[PDF][PDF] Modeling of bacteriophage therapy
JJ Gill - … ecology: population growth, evolution, and impact of …, 2008 - ndl.ethernet.edu.et
Bacteriophage therapy, the treatment of bacterial infections with bacteriophages, is a topic
that has received increasing attention in recent years. While the primary practice of phage …
that has received increasing attention in recent years. While the primary practice of phage …