For early biomaterials, it was required to have a combination of physicochemical properties,
suitable to replace human body tissues and to be biologically inert. Since then a long way …

Disadvantages of conventional drug delivery systems (DDS), such as systemic circulation,
interaction with physiochemical factors, reduced bioavailability, and insufficient drug …

Amorphous calcium phosphates (ACPs) represent a metastable amorphous state of other
calcium orthophosphates (abbreviated as CaPO4) possessing variable compositional but …

Octacalcium phosphate (OCP) belongs to a family of calcium phosphate compounds. OCP
has unique crystal-chemical properties; among calcium phosphate compounds, only OCP …

Traumatic, tumoral, and infectious bone defects are common in clinics, and create a big
burden on patient's families and society. Calcium phosphate (CaP)-based biomaterials have …

Calcium phosphate is the main inorganic component of bone. Calcium phosphate-based
biomaterials have demonstrated great potential in bone tissue engineering due to their …

Various types of grafts have been traditionally used to restore damaged bones. In the late
1960s, a strong interest was raised in studying ceramics as potential bone grafts due to their …

Materials play a key role in several biomedical applications, and it is imperative that both the
materials and biological aspects are clearly understood for attaining a successful biological …

Calcium phosphate (CaP) has traditionally been used for the repair of bone defects because
of its strong resemblance to the inorganic phase of bone matrix. Nowadays, a variety of …

This study hypothesized that distant octacalcium phosphate (OCP) scaffolds may enhance
osteocyte differentiation in newly formed bone matrices. The results obtained were …