Amiodarone-induced thyroid gland dysfunction

S Mechlis, E Lubin, J Laor, M Margaliot… - The American journal of …, 1987 - Elsevier
Of a population of 400 patients treated with amiodarone, 97 underwent thyroid function
evaluation. Of these, 20 patients proved to be thyrotoxic and 16 hypothyroid. In thyrotoxic …

Thyroid dysfunction during chronic amiodarone therapy

SG Albert, LE Alves, EP Rose - Journal of the American College of …, 1987 - Elsevier
Clinical and laboratory features of 99 patients receiving long-term amiodarone therapy were
analyzed to determine which individuals may be at a high risk for developing amiodarone …

Thyrotoxicosis induced by amiodarone, a new efficient antiarrhythmic drug with high iodine content

G Dickstein, S Amikam, E Riss, D Barzilai - The American journal of the …, 1984 - Elsevier
Amiodarone is an antiarrhythmic agent with high iodine content. Ten patients treated with
amiodarone developed thyrotoxicosis. I 131 uptakes were negligible, and TT 3 levels low in …

Effect of long-term amiodarone therapy on thyroid hormone levels and thyroid function

GD Borowski, CD Garofano, LI Rose… - The American journal of …, 1985 - Elsevier
Both hyperthyroidism and hypothyroidism have been noted to occur in some patients treated
with amiodarone for cardiac arrhythmias. To determine the frequency of the development of …

Amiodarone and the thyroid gland. A review.

MH Jonckheer - Acta cardiologica, 1981 - europepmc.org
The author presents his experience with the thyroid complications of amiodarone therapy:
exceptional but sometimes serious conditions. Both, hypo-and hyperthyroidism can occur …

Effects of amiodarone on thyroid function in patients with ischaemic heart disease.

DA Pritchard, BN Singh, PJ Hurley - Heart, 1975 - heart.bmj.com
Thyroid function was evaluated clinically and biochemically in 12 patients with ischaemic
heart disease receiving 200 mg oral amiodarone three times daily for periods up to 6 weeks …

Effects of amiodarone on thyroid function

P Caron - Presse Medicale (Paris, France: 1983), 1995 - europepmc.org
Amiodarone has been used in cardiology for more than 20 years as an anti-angina and anti-
arrhythmia agent. In the seventies, variations in thyroid hormone and TSH concentrations …

Two cases of amiodarone-induced thyrotoxicosis successfully treated with a short course of antithyroid drugs while amiodarone was continued.

MD Trip, DR Düren, WM Wiersinga - Heart, 1994 - heart.bmj.com
Two patients with amiodarone-induced thyrotoxicosis were treated successfully with
potassium perchlorate and carbimazole while treatment with amiodarone was continued …

Amiodarone and thyroid function

K Nademanee, RW Piwonka, BN Singh… - Progress in …, 1989 - Elsevier
Amiodarone blocks the action of thyroid hormone by the inhibition of 5′-deiodinase which
reduces production of T 3 in peripheral tissues and possibly by blocking nuclear binding of T …

Amiodarone, thyroid hormone indexes, and altered thyroid function: long-term serial effects in patients with cardiac arrhythmias

K Nademanee, BN Singh, B Callahan… - The American journal of …, 1986 - Elsevier
Amiodarone, a drug that has electrophysiologic actions resembling those of hypothyroidism,
increases serum levels of T 4 and reverse T 3 (rT 3) and decreases T 3. The drug's long-term …