The mechanistic target of rapamycin (mTOR) is involved in the regulation of cellular growth,
proliferation, lipid synthesis, and protein translation. The mTOR pathway involves two …

The member of the phosphatidylinositol 3-kinase family, mammalian target of rapamycin, is
involved in modulating inflammatory response and regulating cellular processes associated …

The serine/threonine kinase mechanistic target of rapamycin (mTOR) plays a pivotal role in
the regulation of cell proliferation, survival, and motility in response to availability of energy …

The dysregulated phosphatidylinositol-3-kinase (PI3K)-Akt-mammalian target of rapamycin
(mTOR) signaling pathway has been implicated in various immune-mediated inflammatory …

Background In the last years, a clear link between the endocrine signalling also influenced
by Western diet and the pathogenesis of acne has emerged 1, 2. In this context, a crucial …

Background Inhibition of mTOR complex 1 (mTORC1) with rapamycin leads to
phosphorylation of AKT in some cancer cells, with unknown biological consequences. The …

The conserved serine/threonine kinase mammalian target of rapamycin (mTOR) is a major
regulator of survival growth, proliferation and motility, in response to mitogens, energy and …

The mammalian or mechanistic target of rapamycin (mTOR) and associated phosphatidyl-
inositiol 3-kinase (PI3K)/protein kinase B (Akt) pathways regulate cell growth, differentiation …

Psoriasis is a frequent and often severe inflammatory skin disease, characterized by altered
epidermal homeostasis. Since we found previously that Akt/mTOR signaling is …

In this study, we examined the impact of rapamycin on mTORC1 signaling during 12‐O‐
tetradecanoylphorbol‐13‐acetate (TPA)‐induced keratinocyte proliferation and skin tumor …