[HTML][HTML] Novel reinforcement of corrugated nanofiber tissue-engineered vascular graft to prevent aneurysm formation for arteriovenous shunts in an ovine model

H Matsushita, H Hayashi, K Nurminsky, T Dunn… - JVS-Vascular …, 2022 - Elsevier
Objective Many patients who require hemodialysis treatment will often require a prosthetic
graft after multiple surgeries. However, the patency rate of grafts currently available …

Electrospun polyurethane vascular grafts: In vitro mechanical behavior and endothelial adhesion molecule expression

C Grasl, H Bergmeister, M Stoiber… - … Research Part A: An …, 2010 - Wiley Online Library
Engineered small diameter vascular grafts must closely match mechanical characteristics of
native vessels and exhibit stimulus‐responsive bioactivity. In this study, mechanical …

Improvement of a novel small-diameter tissue-engineered arterial graft with heparin conjugation

Y Matsuzaki, S Miyamoto, H Miyachi, R Iwaki… - The Annals of thoracic …, 2021 - Elsevier
Background Small diameter (< 6 mm), bioabsorbable, arterial, tissue-engineered vascular
grafts (TEVGs) remain limited by thromboembolism. The objective of this study was to test …

Electrospun small‐diameter polyurethane vascular grafts: ingrowth and differentiation of vascular‐specific host cells

H Bergmeister, C Grasl, I Walter, R Plasenzotti… - Artificial …, 2012 - Wiley Online Library
No small‐diameter synthetic graft has yet shown comparable performance to autologous
vessels. Synthetic conduits fail due to their inherent surface thrombogenicity and the …

[HTML][HTML] In vitro and in vivo evaluation of a small-caliber coaxial electrospun vascular graft loaded with heparin and VEGF

YT Hu, XD Pan, J Zheng, WG Ma, LZ Sun - International Journal of Surgery, 2017 - Elsevier
Introduction To date, clinically available expanded polytetrafluoro-ethylene (ePTFE)
vascular grafts are suboptimal for reconstructing small caliber (D< 6 mm) arteries, owing to …

Tissue ingrowth markedly reduces mechanical anisotropy and stiffness in fibre direction of highly aligned electrospun polyurethane scaffolds

H Krynauw, J Buescher, J Koehne, L Verrijt… - Cardiovascular …, 2020 - Springer
Purpose The lack of long-term patency of synthetic vascular grafts currently available on the
market has directed research towards improving the performance of small diameter grafts …

In Vivo Applications of Electrospun Tissue-Engineered Vascular Grafts: A Review

KA Rocco, MW Maxfield, CA Best, EW Dean… - … Engineering Part B …, 2014 - liebertpub.com
There is great clinical demand for synthetic vascular grafts with improved long-term efficacy.
The ideal vascular conduit is easily implanted, nonthrombogenic, biocompatible, resists …

Covalent grafting of PEG and heparin improves biological performance of electrospun vascular grafts for carotid artery replacement

T Zhu, H Gu, H Zhang, H Wang, H Xia, X Mo, J Wu - Acta Biomaterialia, 2021 - Elsevier
Rapid endothelialization of small-diameter vascular grafts remains a significant challenge in
clinical practice. In addition, compliance mismatch causes intimal hyperplasia and finally …

Development of biomimetic thermoplastic polyurethane/fibroin small‐diameter vascular grafts via a novel electrospinning approach

E Yu, HY Mi, J Zhang, JA Thomson… - Journal of Biomedical …, 2018 - Wiley Online Library
A new electrospinning approach for fabricating vascular grafts with a layered,
circumferentially aligned, and micro‐wavy fibrous structure similar to natural elastic tissues …

Endothelialization of electrospun polycaprolactone (PCL) small caliber vascular grafts spun from different polymer blends

D Pfeiffer, C Stefanitsch, K Wankhammer… - … Research Part A, 2014 - Wiley Online Library
Small caliber vascular grafts represent a challenge to material scientists. In contrast to large
caliber grafts, prostheses with diameter< 6 mm, lead to increased hemodynamic …