Significance of chimerism in hematopoietic stem cell transplantation: new variations on an old theme

F Khan, A Agarwal, S Agrawal - Bone marrow transplantation, 2004 - nature.com
The main goal of post-transplantation monitoring in hematopoietic stem cell transplantation
(HSCT) is to predict negative events, such as disease relapse, graft rejection and graft …

Strategies and clinical implications of chimerism diagnostics after allogeneic hematopoietic stem cell transplantation

C Thiede, M Bornhäuser, G Ehninger - Acta haematologica, 2004 - karger.com
Abstract Analysis of donor chimerism has become a routine method for the documentation of
engraftment after allogeneic hematopoietic stem cell transplantation (HSCT). In recent years …

Chimerism monitoring techniques after hematopoietic stem cell transplantation: an overview of the last 15 years of innovations

P Tozzo, A Delicati, R Zambello, L Caenazzo - Diagnostics, 2021 - mdpi.com
Chimerism analysis is a well-established method for monitoring the state of hematopoietic
stem cell transplantation (HSCT) over time by analyzing peripheral blood or bone marrow …

How and when should we monitor chimerism after allogeneic stem cell transplantation?

P Bader, D Niethammer, A Willasch… - Bone marrow …, 2005 - nature.com
Chimerism analysis has become an important tool for the peri-transplant surveillance of
engraftment. It offers the possibility to realize impending graft rejection and can serve as an …

Diagnostic value of highly-sensitive chimerism analysis after allogeneic stem cell transplantation

L Sellmann, K Rabe, I Bünting, E Dammann… - Bone marrow …, 2018 - nature.com
Conventional analysis of host chimerism (HC) frequently fails to detect relapse before its
clinical manifestation in patients with hematological malignancies after allogeneic stem cell …

The EuroChimerism concept for a standardized approach to chimerism analysis after allogeneic stem cell transplantation

T Lion, F Watzinger, S Preuner, H Kreyenberg… - Leukemia, 2012 - nature.com
Hematopoietic stem cell transplantation is becoming an increasingly important approach to
treatment of different malignant and non-malignant disorders. There is thus growing demand …

Chimerism analysis for clinicians: a review of the literature and worldwide practices

AG Blouin, M Askar - Bone marrow transplantation, 2022 - nature.com
This review highlights literature pertinent to chimerism analysis in the context of
hematopoietic cell transplantation (HCT). We also conducted a survey of testing practices of …

Chimerism analysis within 6 months of allogeneic stem cell transplantation predicts relapse in acute myeloid leukemia

C Huisman, RA De Weger, L De Vries… - Bone marrow …, 2007 - nature.com
The role of chimerism analysis as a prognostic indicator of relapse after hematopoietic stem
cell transplantation (SCT) is controversial. We monitored chimerism status by short tandem …

Quantitative assessment of hematopoietic chimerism after bone marrow transplantation by real-time quantitative polymerase chain reaction

M Alizadeh, M Bernard, B Danic… - Blood, The Journal …, 2002 - ashpublications.org
We have developed a real-time quantitative polymerase chain reaction (PCR) assay using
TaqMan technology (Applied Biosystems, Foster City, CA) for monitoring donor cell …

Studies on hemopoietic chimerism following allogeneic bone marrow transplantation in the molecular biology era

G Socie, M Lawler, E Gluckman, SR McCann… - Leukemia research, 1995 - Elsevier
Donor hematopoiesis or donor chimerism in the host following allogeneic bone marrow
transplantation (BMT) has appeared crucial to the engraftment process. However, as …