Correlating changes in lung function with patient outcomes in chronic obstructive pulmonary disease: a pooled analysis
PW Jones, JF Donohue, J Nedelman, S Pascoe… - Respiratory …, 2011 - Springer
Background Relationships between improvements in lung function and other clinical
outcomes in chronic obstructive pulmonary disease (COPD) are not documented …
outcomes in chronic obstructive pulmonary disease (COPD) are not documented …
Treatment response in COPD: does FEV1 say it all? A post hoc analysis of the CRYSTAL study
K Kostikas, T Greulich, AJ Mackay, NS Lossi… - ERJ open …, 2019 - Eur Respiratory Soc
The association between clinically relevant changes in patient-reported outcomes (PROs)
and forced expiratory volume in 1 s (FEV1) in patients with chronic obstructive pulmonary …
and forced expiratory volume in 1 s (FEV1) in patients with chronic obstructive pulmonary …
Measuring disease activity in COPD: is clinically important deterioration the answer?
D Singh, GJ Criner, I Naya, PW Jones, L Tombs… - Respiratory …, 2020 - Springer
Given the heterogeneity of chronic obstructive pulmonary disease (COPD), personalized
clinical management is key to optimizing patient outcomes. Important treatment goals …
clinical management is key to optimizing patient outcomes. Important treatment goals …
Exacerbation frequency and course of COPD
DMG Halpin, M Decramer, B Celli… - … journal of chronic …, 2012 - Taylor & Francis
Background Exacerbations affect morbidity in chronic obstructive pulmonary disease
(COPD). We sought to evaluate the association between exacerbation frequency and …
(COPD). We sought to evaluate the association between exacerbation frequency and …
Assessment tools for chronic obstructive pulmonary disease: do newer metrics allow for disease modification?
DA Mahler, GJ Criner - Proceedings of the American Thoracic …, 2007 - atsjournals.org
The change in FEV1 has been the traditional metric used to define the progression of
chronic obstructive pulmonary disease in affected patients. Consequently, various …
chronic obstructive pulmonary disease in affected patients. Consequently, various …
Characteristics associated with accelerated lung function decline in a primary care population with chronic obstructive pulmonary disease
HR Whittaker, JM Pimenta, D Jarvis… - … journal of chronic …, 2020 - Taylor & Francis
Background Estimates for lung function decline in chronic obstructive pulmonary disease
(COPD) have differed by study setting and have not been described in a UK primary care …
(COPD) have differed by study setting and have not been described in a UK primary care …
Pharmacotherapy and lung function decline in patients with chronic obstructive pulmonary disease. A systematic review
BR Celli, JA Anderson, NJ Cowans, C Crim… - American journal of …, 2021 - atsjournals.org
Rationale: Whether pharmacological therapy alters decline in FEV1 in chronic obstructive
pulmonary disease remains controversial. Because pharmacotherapy improves health …
pulmonary disease remains controversial. Because pharmacotherapy improves health …
Lung function decline in COPD trials: bias from regression to the mean
S Suissa - European Respiratory Journal, 2008 - Eur Respiratory Soc
The decline in lung function over time is a fundamental measure of disease progression
among patients with chronic obstructive pulmonary disease (COPD). As a result, forced …
among patients with chronic obstructive pulmonary disease (COPD). As a result, forced …
[HTML][HTML] Effect of a single exacerbation on decline in lung function in COPD
DMG Halpin, M Decramer, BR Celli, A Mueller… - Respiratory …, 2017 - Elsevier
Background COPD exacerbations are associated with accelerated lung function decline, but
whether they are causal is unknown. We evaluated the effect of a single exacerbation on …
whether they are causal is unknown. We evaluated the effect of a single exacerbation on …
Impact of lung function and exacerbations on health-related quality of life in COPD patients within one year: real-world analysis based on claims data
A Stöber, JI Lutter, L Schwarzkopf, F Kirsch… - … journal of chronic …, 2021 - Taylor & Francis
Purpose Real-world evidence on the impact of forced expiratory volume in one second
(FEV1) and exacerbations on health-related quality of life (HRQoL) in patients with chronic …
(FEV1) and exacerbations on health-related quality of life (HRQoL) in patients with chronic …
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