Next generation sequencing (NGS) technology is rapidly being implemented into clinical
practice. Qualitative research was performed to gain an improved understanding of the …

Background Germline variant evaluation in precision oncology opens new paths toward the
identification of patients with genetic tumor risk syndromes and the exploration of therapeutic …

The field of cancer genetics is evolving rapidly, and much has changed over the past ten
years in the way services are being provided and by whom they are being provided. We …

Hereditary cancer syndromes result from germline genetic alterations predisposing
individuals to higher lifetime cancer risk than the general population. Hereditary cancer …

Significant strides have been made in cancer surveillance for children with hereditary cancer
predisposition syndromes. A continued emphasis on consensus-driven screening …

As a result of the increasing effectiveness of cancer screening and preventive interventions,
ethical issues, as well as legal liabilities, are increasingly associated with cancer genetic …

Genetic testing for hereditary cancer predisposition has evolved rapidly in recent years with
the discovery of new genes, but there is much debate over the clinical utility of testing genes …

Cancer genetic counseling practice is rapidly evolving, with services being provided in
increasingly novel ways. Pretest counseling for cancer patients may be abbreviated from …

Advances in the understanding of cancer predisposition and implementation of standardized
cancer surveillance protocols have improved the outcome for certain patients. Future …

▪ Abstract Clinical cancer genetics is becoming an integral part of the care of cancer patients.
This review describes the clinical aspects, genetics, and clinical genetic management of …