Hypertonic versus isotonic salt bridges in ion-selective electrode based clinical analysers

P D'Orazio, D Verghese - Annals of Clinical Biochemistry, 1991 - journals.sagepub.com
Two recent papers by Payne et a1.'S2 propose that an isotonic salt bridge of either 150
mmol/L KCl or NaCl may lead to improvements in performance over the hypertonic salt …

Protein interference with ion-selective electrode measurement depends on reference electrode composition and design

RB Payne, BM Buckley… - Annals of clinical …, 1991 - journals.sagepub.com
There is controversy about whether protein interferes with ion measurements using ion-
selective electrodes. We have investigated the effects of changes in the salt-bridge …

[引用][C] The apparent suppression of Na/K data obtained with ion-selective electrodes is due to junction potential and activity coefficient effects, not bicarbonate binding.

JD Czaban, AD Cormier, KD Legg - Clinical chemistry, 1982 - academic.oup.com
Biomedical, Newton, MA) ion-selective electrode type of analyzer relative to that obtained
with flame photometry. They were concerned because their results were in disagreement …

Effects of ionic strength on ionized calcium measured using reference electrode liquid junctions of varying design and composition

RB Payne - Annals of clinical biochemistry, 1991 - journals.sagepub.com
Five commercial analysers were used to measure ionized calcium in aqueous and protein
solutions which contained the same amount of calcium but had sodium chloride …

Why plasma electrolytes?

DB Morgan - Annals of Clinical Biochemistry, 1981 - journals.sagepub.com
The real value of the budget available for clinical chemistry in this country is unlikely to
increase for some years. Any expansion and development must therefore be balanced by …

[引用][C] Nova 2 ionized calcium analyzer: imprecision, bias, and protein interference.

SJ Butler, RB Payne - Clinical chemistry, 1983 - academic.oup.com
3. Payne RB. Clinically significant effect of protein concentration on ion-selective electrode
measurements of ionised calcium. Ann Clin Biochem 19, 233-237 (1982). 4. Payne RB, Little …

Protein interferes with ionised calcium measurement at the reference electrode liquid junction

RB Payne, DP Jones - Annals of clinical biochemistry, 1987 - journals.sagepub.com
The ionised calcium concentration of sequential retentates prepared by ultrafiltration of a
human control serum increased with increasing protein concentration when measured with …

Clinically significant effect of protein concentration on ion-selective electrode measurements of ionised calcium

RB Payne - Annals of Clinical Biochemistry, 1982 - journals.sagepub.com
Others, using an Orion SS-20 ionised calcium analyser, noted that the ionised calcium
concentration of a native serum sample was 8% greater than that of its ultrafiltrate. The …

Bicarbonate interference with chloride-ion-selective electrodes

G Dimeski, AE Clague - Clinical chemistry, 2004 - academic.oup.com
Plasma chloride is of value in the assessment of acid/base and electrolyte abnormalities. It is
a component in calculation of both the anion gap and strong ion differences. The analytical …

An isotonic potassium chloride liquid junction minimises the effects of ionic strength, protein and haematocrit on ionised calcium measurement

RB Payne - Annals of clinical biochemistry, 1988 - journals.sagepub.com
When the reference electrode liquid junction of a Nova 2 analyser was changed to isotonic
potassium chloride, increasing the ionic strength of aqueous solutions containing a constant …