Human cytomegalovirus (HCMV), a member of an ancient family of viruses (Herpesviridae),
has acquired the capacity to maintain a lifelong persistent infection within an …

Human cytomegalovirus (HCMV) establishes and maintains a lifelong persistence following
infection in an immunocompetent host. The determinants of a stable virus-host relationship …

Highlights•Nonhuman primate (NHP) CMVs are most closely related to human CMV
(HCMV).•Rhesus CMV (RhCMV) bears numerous genomic and functional similarities to …

Cytomegaloviruses (CMVs) are highly adapted to their host species resulting in strict
species specificity. Hence, in vivo examination of all aspects of CMV biology employs animal …

Congenital human cytomegalovirus (HCMV) infection has long been recognized as a threat
to the developing fetus, even though studies have shown that only a subset of congenital …

The natural history of human cytomegalovirus (HCMV) is inextricably associated with
mucosal surfaces. The vast preponderance of primary infections occur following mucosal …

Implicit with the use of animal models to test human cytomegalovirus (HCMV) vaccines is the
assumption that the viral challenge of vaccinated animals reflects the anticipated virus-host …

Cytomegalovirus (CMV) is a highly species-specific virus that has co-evolved with its host
over millions of years and thus restricting cross-species infection. To examine the extent to …

Human cytomegalovirus (HCMV) is a leading viral cause of congenital infections in the
central nervous system (CNS) and may result in severe long-term sequelae. High rates of …

As with all herpesviruses, human cytomegalovirus (HCMV) can establish lifelong
persistence after primary infection, with reactivation occurring often as a result of …