Background: Esterase is an enzyme that splits esters into an acid and alcohol. Varieties of
esterases are present in human body to control diverse set of cellular processes and …

Mammalian carboxylesterases are key serine hydrolases that catalyze the hydrolysis of a
wide variety of ester compounds in the corresponding carboxylic acids and alcohols. In …

Mammalian carboxylesterases are key serine hydrolases that catalyze the hydrolysis of a
wide variety of ester compounds in the corresponding carboxylic acids and alcohols. In …

Synthetic chemistry and drug design through different software is becoming more and more
important nowadays. In this modern era each person is suffering from many diseases due to …

An enhanced acetylcholinesterase (AChE) activity is a hallmark in early stages of
Alzheimer's ailment that results in decreased acetylcholine (ACh) levels, which in turn leads …

New drug discovery is considered broadly in terms of two kinds of investigational activities
such as exploration and exploitation. This study deals with the evaluation of the cholesterol …

Nowadays, esterases represent high growth potential in the World Industrial Enzymes
Market. The industrial applications of esterases provide an immense contribution to the eco …

Inhibition profiles of synthesized 4‐methyl benzene sulfonamide derivatives on carbonic
anhydrase I (CA I) and II (CA II), acetylcholinesterase (AChE) and butyrylcholinesterase …

In our search for natural human carboxylesterase 2 (hCE 2) inhibitors from natural products,
we investigated inhibitory effects and mechanisms of flavonoids (1–16) against hCE 2. The …

Novel N-substituted phthalimide derivatives (4a–c) were synthesized using a three-step
procedure in high yields. The inhibitory effects of these compounds against Electric eel …