The Biology and Molecular Biology Underlying Epstein-Barr Virus Oncogenesis

HJ Martin, SD Hayward - Human Cancer Viruses, 2008 - karger.com
Epstein-Barr virus (EBV) is a ubiquitous-herpesvirus. After exposure, individuals remain EBV-
infected for life. EBV-infected B cells are the primary site of in vivo persistence but mucosal …

Epstein–Barr virus and oncogenesis: from latent genes to tumours

LS Young, PG Murray - Oncogene, 2003 - nature.com
Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus associated with the
development of both lymphoid and epithelial tumours. As a common virus infection, EBV …

[HTML][HTML] The expression and function of Epstein-Barr virus encoded latent genes

LS Young, CW Dawson, AG Eliopoulos - Molecular Pathology, 2000 - ncbi.nlm.nih.gov
Abstract The association of Epstein-Barr virus (EBV) with various malignancies is well
established but the pattern of EBV latent gene expression in these different tumours is …

Role of the latent genes of Epstein-Barr virus in the oncogenesis.

MAP Lima, SHB Rabenhorst - 2010 - cabidigitallibrary.org
Epstein-Barr virus (EBV) is widely distributed around the world, being estimated that more
than 90% of the adult population is infected and that the majority transmits intermittently by …

[HTML][HTML] Epstein-Barr virus: clinical and epidemiological revisits and genetic basis of oncogenesis

AS Ali, M Al-Shraim, AM Al-Hakami… - The open virology …, 2015 - ncbi.nlm.nih.gov
Epstein-Barr virus (EBV) is classified as a member in the order herpesvirales, family
herpesviridae, subfamily gammaherpesvirinae and the genus lymphocytovirus. The virus is …

Epstein–Barr Virus: Molecular Biology

JT Sample, C Sample - Encyclopedia of Virology: Volume 1-5, 2008 - pure.psu.edu
Epstein–Barr virus (EBV) is a potent transformer of B lymphocytes in vitro and is associated
with a half dozen human cancers. Yet, while 90% of the world population is persistently …

Epstein-Barr virus latency: current and future perspectives

B Kempkes, ES Robertson - Current Opinion in Virology, 2015 - Elsevier
Highlights•EBV is an oncogenic gammaherpesvirus that transforms human primary B-
cells.•EBV encoded transcription factors assemble at primed enhancers to activate cell …

Epstein-Barr virus: Mechanisms of oncogenesis

L Karimi, DH Crawford - DNA Tumor Viruses: Oncogenic Mechanisms, 1995 - Springer
Abstract Epstein-Barr virus (EBV), like all human herpesviruses, infects almost all of the
world's population with an asymptomatic or trivial primary infection followed by lifelong …

[HTML][HTML] Epigenetic Mechanisms in Latent Epstein-Barr Virus Infection and Associated Cancers

AS Torne, ES Robertson - Cancers, 2024 - mdpi.com
Simple Summary Epstein–Barr virus (EBV) was first isolated in 1964 and has since become
an important human tumor virus. With an estimated 90% of the human population infected …

Epstein-Barr virus infection and the pathogenesis of malignant lymphomas.

G Niedobitek, LS Young, H Herbst - Cancer surveys, 1997 - europepmc.org
EBV is associated with an ever increasing number of human malignancies, which illustrates
the importance of understanding how the virus contributes to tumorigenesis. Recent work …