Lichens are a known source of approximately 800 unique secondary metabolites, many of
which play important ecological roles, including regulating the equilibrium between …

One of the ways for searching for potentially new anti-cancer drugs is the testing of various
naturally synthesized compounds. Lichens are a source of unique chemical agents of which …

Usnic acid (UA), an active dibenzofuran derivative mainly found in lichens, is considered an
antineoplastic agent based on its activity against tumor cells. However, the exact molecular …

Lichens are symbiotic organisms which produce distinct secondary metabolic products. In
the present study, we tested the cytotoxic activity of 17 lichen species against several human …

The purpose of this study was to investigate the effects of six lichen metabolites (diffractaic
acid, lobaric acid, usnic acid, vicanicin, variolaric acid, protolichesterinic acid) on …

The presence of uninhibited side effects of cancer drugs often used in cancer treatment has
stimulated the search for alternative therapeutic approaches. Therefore, anticarcinogenic …

Objectives and methods Lichens are an interesting source of potential anti-tumor
compounds, among which usnic acid and atranorin seem to be the most promising, but their …

Usnic acid, a dibenzofuran derivative found in many lichen species, is reported to have
anticancer activity against human gastric cancer. We investigated the molecular alterations …

Lung squamous cell carcinoma (LUSC) has a poor prognosis, in part due to poor
therapeutic response and limited therapeutic alternatives. Lichens are symbiotic organisms …

Lichens produce different classes of phenolic compounds, including anthraquinones,
xanthones, dibenzofuranes, depsides and depsidones. Many of them have revealed …