Objective—We have previously demonstrated that endothelial xanthine oxidase (XO) levels
are dependent on the NADPH oxidase. We postulated that H2O2 may modulate the …

The contribution of xanthine oxidoreductase (XDH+ XO) to the extracellular release of
hydrogen peroxide (H 2 O 2) and intracellular H 2 O 2 concentration in cultured bovine aortic …

We have previously reported that endothelial cell (EC) xanthine dehydrogenase/xanthine
oxidase (XD/XO) activity correlates inversely with the O2 tension to which the cells are …

Concentrations of up to 1.5 milliunits/ml xanthine oxidase (XO)(1.1 μg/ml) are found
circulating in plasma during diverse inflammatory events. The saturable, high affinity binding …

The present study determined the effect of hypoxia on xanthine dehydrogenase (XDH) and
xanthine oxidase (XO) activity and gene and protein expression in cultured bovine aortic …

Xanthine oxidase (XO) is a critical source of reactive oxygen species (ROS) in inflammatory
disease. Focus, however, has centered almost exclusively on XO-derived superoxide …

The conversion of xanthine dehydrogenase (XDH) to xanthine oxidase (XO) and the
reaction of XO-derived partially reduced oxygen species (PROS) have been suggested to be …

Recent studies have demonstrated that xanthine dehydrogenase/xanthine oxidase (XD/XO)
activities of bovine endothelial cells (EC) are inversely regulated by O2 tensions to which the …

Xanthine oxidoreductase (XOR) activity has been previously noted to be responsive to
changes in O2 tension. While prior studies have focused on the extremes (0–3% and 95 …

Xanthine oxidoreductase (XOR) is a ubiquitous metalloflavoprotein that appears in two
interconvertible yet functionally distinct forms: xanthine dehydrogenase (XD), which is …