miR-29b ameliorates atrial fibrosis in rats with atrial fibrillation by targeting TGFβRΙ and inhibiting the activation of Smad-2/3 pathway
X Han, S Wang, Z Yong, X Zhang, X Wang - Journal of Bioenergetics and …, 2022 - Springer
Objective Atrial fibrillation (AF) is a major cause of stroke with lifetime risks. microRNAs
(miRNAs) are associated with AF attenuation, yet the mechanism remains unknown. This …
(miRNAs) are associated with AF attenuation, yet the mechanism remains unknown. This …
Atrial overexpression of microRNA-27b attenuates angiotensin II-induced atrial fibrosis and fibrillation by targeting ALK5
Y Wang, H Cai, H Li, Z Gao, K Song - Human Cell, 2018 - Springer
Atrial fibrosis influences atrial fibrillation (AF) development by transforming growth factor
beta 1 (TGF-β1)/Smad pathway. Although microRNAs are implicated in the pathogenesis of …
beta 1 (TGF-β1)/Smad pathway. Although microRNAs are implicated in the pathogenesis of …
Modulation of miR-10a-mediated TGF-β1/Smads signaling affects atrial fibrillation-induced cardiac fibrosis and cardiac fibroblast proliferation
PF Li, RH He, SB Shi, R Li, QT Wang, GT Rao… - Bioscience …, 2019 - portlandpress.com
Atrial fibrillation (AF) rat models and rat cardiac fibroblasts (CFs) with overexpressed or
inhibited miR-10a were used to investigate the possible role of miR-10a-mediated …
inhibited miR-10a were used to investigate the possible role of miR-10a-mediated …
Overexpression of MiR‐29b‐3p Inhibits Atrial Remodeling in Rats by Targeting PDGF‐B Signaling Pathway
X Lv, P Lu, Y Hu, T Xu - Oxidative Medicine and Cellular …, 2021 - Wiley Online Library
Purpose. Studies have found that microRNAs (miRNAs) are closely associated with atrial
fibrillation, but their specific mechanism remains unclear. The purpose of this experiment is …
fibrillation, but their specific mechanism remains unclear. The purpose of this experiment is …
miR-15a-5p regulates myocardial fibrosis in atrial fibrillation by targeting Smad7
D He, Z Ruan, G Song, G Chen, F Wang, M Wang… - PeerJ, 2021 - peerj.com
Background At present, there is no effective treatment for myocardial fibrosis in atrial
fibrillation (AF). It is reported that miR-15a-5p is abnormally expressed in AF patients but its …
fibrillation (AF). It is reported that miR-15a-5p is abnormally expressed in AF patients but its …
MiR-324-3p regulates fibroblast proliferation via targeting TGF-β1 in atrial fibrillation
J Xu, S Lei, S Sun, W Zhang, F Zhu, H Yang… - International Heart …, 2020 - jstage.jst.go.jp
Atrial fibrillation (AF), one of the common clinical arrhythmias, lacks effective treatment
manners. Cardiac fibroblasts play an essential role in myocardial fibrosis and cardiac …
manners. Cardiac fibroblasts play an essential role in myocardial fibrosis and cardiac …
miR‐135a Regulates Atrial Fibrillation by Targeting Smad3
X Fan, K Feng, Y Liu, L Yang, Y Zhao… - Cardiovascular …, 2023 - Wiley Online Library
Background. Atrial fibrillation (AF) is the most common arrhythmia in clinical. Atrial fibrosis is
a hallmark feature of atrial structural remodeling in AF, which is regulated by the TGF …
a hallmark feature of atrial structural remodeling in AF, which is regulated by the TGF …
Overexpression of miR‐27b‐3p Targeting Wnt3a Regulates the Signaling Pathway of Wnt/β‐Catenin and Attenuates Atrial Fibrosis in Rats with Atrial Fibrillation
X Lv, J Li, Y Hu, S Wang, C Yang, C Li… - … Medicine and Cellular …, 2019 - Wiley Online Library
MicroRNAs (miRNAs) are regarded as a potential method for the treatment of atrial
fibrillation (AF) although its molecular mechanism remains unknown. We found in our …
fibrillation (AF) although its molecular mechanism remains unknown. We found in our …
Novel role of the clustered miR‐23b‐3p and miR‐27b‐3p in enhanced expression of fibrosis‐associated genes by targeting TGFBR3 in atrial fibroblasts
Z Yang, Z Xiao, H Guo, X Fang, J Liang… - Journal of Cellular …, 2019 - Wiley Online Library
Atrial fibrillation (AF) is the most common type of arrhythmia in cardiovascular diseases.
Atrial fibrosis is an important pathophysiological contributor to AF. This study aimed to …
Atrial fibrosis is an important pathophysiological contributor to AF. This study aimed to …
MicroRNA‐146b‐5p promotes atrial fibrosis in atrial fibrillation by repressing TIMP4
Q Ye, Q Liu, X Ma, S Bai, P Chen… - Journal of Cellular …, 2021 - Wiley Online Library
Alteration of tissue inhibitors of matrix metalloproteinases (TIMP)/matrix metalloproteinases
(MMP) associated with collagen upregulation has an important role in sustained atrial …
(MMP) associated with collagen upregulation has an important role in sustained atrial …
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