Abstract Background Long non-coding RNAs (lncRNA) plasmacytoma variant translocation
1 (PVT1) has been shown to be associated with liver fibrosis. Nevertheless, the role of PVT1 …

Cardiac fibroblasts proliferation is the most important pathophysiological character of
cardiac fibrosis while the underlying mechanisms are still incompletely known. MicroRNAs …

MicroRNAs (miR) have considerable potential as therapeutic tools in cardiac diseases.
Alterations in atrial miR are involved in the development of atrial fibrillation (AF), but the …

Objective: New drugs to block the occurrence of atrial fibrillation (AF) based on atrial
structural remodeling (ASR) are urgently needed. The purpose of this study was to study the …

We investigated the effects of microRNA-587b (miR-487b) in a rat model of chronic heart
failure (CHF). Wistar rats were assigned to 10 groups (n= 8 per group). Expression of …

MiR‐27 prevents atherosclerosis by inhibiting inflammatory responses induced by
lipoprotein lipase. Overexpression of miR‐27b attenuates angiotensin‐induced atrial …

Aims The present study was designed to decipher molecular mechanisms underlying
nicotine's promoting atrial fibrillation (AF) by inducing atrial structural remodelling. Methods …

Cardiac fibrosis with diabetic nephropathy (DN) is one of major diabetic complications. miR-
21 and MMP-9 were closely associated with fibrosis diseases. Angiotensin II receptor …

Background/Aims: Asthma is a heterogeneous disease characterized by chronic airway
inflammation resulting from airway hyper-responsiveness to diverse stimuli. In this study, we …

Objective: Airway remodeling is an important pathological feature of asthma. Excessive
deposition of extracellular matrix (eg, collagen) secreted from fibroblasts is a major factor …