Ovarian cancer (OVCA) arises from three cellular origins, namely surface epithelial cells,
germ cells, and stromal cells. More than 85% of OVCAs are EOCs (epithelial ovarian …

Emerging evidence has suggested that androgen receptor signaling plays an important role
in ovarian cancer outgrowth. Specifically, androgen receptor activation appears to be …

Ovarian cancer is the major cause of death in women with gynecologic malignancies. There
is emerging evidence that Androgen/androgen receptor (AR) signaling plays a critical role in …

There are three main types of cancer in the female reproductive system, specifically ovarian
cancer (OVCA), endometrial cancer (EC), and cervical cancer (CC). They are common …

Endometrial cancer (EC) and ovarian cancer are common gynaecological malignancies.
The impact of androgen action in these cancers is poorly understood; however, there is …

Background Ovarian teratocarcinoma (OVTC) arises from germ cells and contains a high
percentage of cancer stem/progenitor cells (CSPCs), which promote cancer development …

Ovarian cancer is one of the most lethal malignancies in women. Numerous studies indicate
that the steroid hormones have been implicated in the etiology and/or progression of …

Abstract Learning Objectives After completing this course, the reader will be able to: Explain
the role of the androgen axis in the development of ovarian cancer. Discuss the potential …

OBJECTIVES: In the present study we explore the effects of androgens and anti-androgens
on primary cultures of EOC cells. We also investigate the effects of chemotherapy on AR …

Background Altered androgen hormone homeostasis and androgen receptor (AR) activity
have been implicated in ovarian carcinogenesis but the relationship between AR expression …