In the human, the molybdenum cofactor (MoCo) is a cofactor for sulfite oxidase, aldehyde
oxidase, xanthine dehydrogenase, and for the mitochondrial amidoxime-reducing …

Water transport is inextricably linked to a number of brain functions (Agre et al., 2002; Amiry-
Moghaddam et al., 2003a; Kimelberg, 2004). On the macroscopic scale, the production and …

Thiamine deficiency (TD) is accepted as the cause of beriberi because of its action in the
metabolism of simple carbohydrates, mainly as the rate limiting cofactor for the …

Sulfite oxidase deficiency (SOD) and related disorders, especially molybdenum cofactor
deficiency (MoCD), are a group of rare and severe neurometabolic disorders caused by …

The emerging research on biomarkers in alcohol dependence has lead to a deeper
understanding of the neurobiological mechanisms in alcoholism. The molecular networks …

Reductions in brain glucose metabolism and increased oxidative stress invariably occur in
Alzheimer's disease (AD) and thiamine (vitamin B1) deficiency. Both conditions cause …

In plasma of mothers with a child affected with a neural tube defect plasma homocysteine is
often elevated, and attributed to a reduced folate-dependent homocysteine remethylation …

Inherited disorders of amino and organic acid metabolism have a high cumulative
frequency, and despite heterogeneous aetiology and varying clinical presentation, the …

In addition to the priority in the discovery of the first water channel protein in the red blood
cell membrane the group of Gheorghe Benga in Cluj-Napoca, Romania, also has a world …

The molecular basis for the physiology of the brain has advanced enormously in the past
twenty years with an influx of new information gleaned through technological developments …