Species of Filobasidiella, the agents of cryptococcosis, produced melanin-like pigments
within 4 to 48 h with diphenol, aminophenol, and diaminobenzene compounds as …

Several indoles served as substrates for the phenoloxidase of Cryptococcus neoformans
and resulted in the production of a melanin-like pigment. In general, a higher percentage of …

Cryptococcus neoformans and other Cryptococcus species can produce pigment (s) from
many aminophenol and diaminobenzene compounds. Pigment production from these …

Cryptococcus neoformans produced pigments when p-diphenols were substrates in a
glucose-amino acid-salts medium. The best substrates were 2.5-dihydroxybenzoic acid and …

Melanogenesis in Cryptococcus neoformans begins with the oxidation of
dihydroxyphenylalanine by the enzyme phenol oxidase. The succeeding steps are very …

Pigment production by Cryptococcus neoformans is virulence associated. Dopamine-and 3,
4-dihydroxyphenylalanine–melanin products were identified after acidic permanganate …

Melanin is a recognized virulence factor in Cryptococcus neoformans; several pathogenetic
mechanisms have been suggested. We studied melanin as an antifungal resistance factor …

Genetic analyses using a melanin-negative mutant and a wild type showed that the ability to
form melanin on L-DOPA or Guizotia media was unrelated to mating type. The rates of in …

The laccase enzyme and melanin synthesis have been implicated as contributors to
virulence in Cryptococcus neoformans. Since isolations of Cryptococcus species other than …

A double mutant of Cryptococcus neoformans which lacked the ability to produce melanin
(Mel-) on media containing diphenols and failed to grow at 37 degrees C (temperature …