Ellagic acid prevents rat colon carcinogenesis induced by 1, 2 dimethyl hydrazine through inhibition of AKT-phosphoinositide-3 kinase pathway

S Umesalma, G Sudhandiran - European journal of pharmacology, 2011 - Elsevier
Colon cancer is the third most malignant neoplasm in the world and chemoprevention
through dietary intervention is an emerging option to reduce its mortality. Ellagic acid (EA) a …

Antiproliferative and apoptotic-inducing potential of ellagic acid against 1, 2-dimethyl hydrazine-induced colon tumorigenesis in Wistar rats

S Umesalma, P Nagendraprabhu… - Molecular and cellular …, 2014 - Springer
Colon cancer remains one of the major worldwide causes of cancer-related morbidity and
mortality in Western countries and is increasingly common in Asia. Ellagic acid (EA), a major …

Ellagic acid inhibits proliferation and induced apoptosis via the Akt signaling pathway in HCT-15 colon adenocarcinoma cells

S Umesalma, P Nagendraprabhu… - Molecular and cellular …, 2015 - Springer
Chemoprevention is regarded as one of the most promising and realistic approaches in the
prevention of human cancer. Ellagic acid (EA) has been known for its chemopreventive …

Ellagic acid promotes A549 cell apoptosis via regulating the phosphoinositide 3‑kinase/protein kinase B pathway

Q Liu, X Liang, C Niu, X Wang - Experimental and …, 2018 - spandidos-publications.com
The present study aimed to evaluate the anti‑cancer effect of ellagic acid in human non‑
small cell lung cancer (NSCLC) A549 cells and to reveal the potential underlying …

Ellagic acid checks lymphoma promotion via regulation of PKC signaling pathway

S Mishra, M Vinayak - Molecular Biology Reports, 2013 - Springer
Abstract Protein Kinase C (PKC) isozymes are key components involved in cell proliferation
and their over activation leads to abnormal tumor growth. PKC follows signalling pathway by …

Ellagic acid induced p53/p21 expression, G1 arrest and apoptosis in human bladder cancer T24 cells

TM Li, GW Chen, CC Su, JG Lin, CC Yeh… - Anticancer …, 2005 - ar.iiarjournals.org
It is well known that dietary phenolic compounds can elicit vital cellular responses such as
cytotoxicity, cell cycle arrest and apoptosis by activating a cascade of molecular events …

[PDF][PDF] Ellagic acid-chemopreventive role in oral cancer

PS Bisen, SS Bundela, A Sharma - J Cancer Sci Ther, 2012 - academia.edu
Ellagic acid is an antioxidant and an anti-proliferative compound present in fruits, nuts and
vegetables. In spite of evidences for anticancer activity in various cancer cell-lines, human …

[HTML][HTML] Ellagic acid induces apoptosis through inhibition of nuclear factor κB in pancreatic cancer cells

M Edderkaoui, I Odinokova, I Ohno… - World Journal of …, 2008 - ncbi.nlm.nih.gov
AIM: To determine the effect of ellagic acid on apop-tosis and proliferation in pancreatic
cancer cells and to determine the mechanism of the pro-survival effects of ellagic acid …

Ellagic acid induces apoptosis in TSGH8301 human bladder cancer cells through the endoplasmic reticulum stress‐and mitochondria‐dependent signaling pathways

CC Ho, AC Huang, CS Yu, JC Lien… - Environmental …, 2014 - Wiley Online Library
To investigate the effects of ellagic acid on the growth inhibition of TSGH8301 human
bladder cancer cells in vitro, cells were incubated with various doses of ellagic acid for …

Ellagic acid induces HeLa cell apoptosis via regulating signal transducer and activator of transcription 3 signaling

LW Li, C Na, SY Tian, J Chen… - Experimental and …, 2018 - spandidos-publications.com
Ellagic acid has been reported to possess various activities, including anti-inflammatory, anti-
oxidative, antiviral and anticancer abilities. However, the effect and underlying molecular …